| RAEB-T | Refractory Anemia with Excess Blasts in Transformation |
|---|---|
| ALPG | alkaline phosphatase, germ-cell |
| ATZ | atypical transformation zone |
| ELECTZ | electrosurgical loop excision of the cervical transformation zone |
| GA | Gamblers Anonymous; gastric analysis; gastric antrum; general anesthesia; general angiography; gener... |
| transformation | <chemistry> The change of form or structure, conversion from one form to another. <oncology> The change that a normal cell undergoes as it becomes malignant. In eukaryotes, the conversion of normal cells to malignant cells in cell culture. Origin: L. Formatio = formation (18 Nov 1997) |
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| transformation, bacterial | The heritable modification of the properties of a competent bacterium by DNA from another bacterial strain. (12 Dec 1998) |
| transformation constant | <physics, radiobiology> The fraction of the amount of a radionuclide that undergoes transition per unit time. Formally: Lamda=dP/dt Where dP is the probability of a given nucleus undergoing spontaneous nuclear transition in the time interval dt. (16 Dec 1997) |
| transformation efficiency | The number of bacterial cells that uptake and express plasmid DNA divided by the mass of plasmid used (in transformants/microgram). (09 Oct 1997) |
| transformation, genetic | The unidirectional transfer and incorporation of foreign DNA by prokaryotic or eukaryotic cells and the subsequent recombination of part or all of that DNA into the cell's genome. (glossary of genetics: classical and molecular, 5th ed) (12 Dec 1998) |
| transformation zone | Zone on the cervix at which squamous epithelium and columnar epithelium meet; changes location in response to a woman's hormonal status. (05 Mar 2000) |
| Lobry de Bruyn-van Ekenstein transformation | The conversion of glucose to fructose and mannose in dilute alkali by enolization adjacent to the carbonyl group to form an enediol, a reaction analogous to certain biochemical transformations. (05 Mar 2000) |
| logit transformation | A method of linearizing dose-response curves for radioimmunoassay techniques; i.e., Logit B (bound)/Bo(initial binding) = Log (B/Bo/1-B/Bo). (05 Mar 2000) |
| lymphocyte transformation | <haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associated with oncogenic viruses and activation is therefore perhaps a better term. (18 Nov 1997) |
| germ | 1. <biology> That which is to develop a new individual; as, the germ of a foetus, of a plant or flower, and the like; the earliest form under which an organism appears. "In the entire process in which a new being originates . Two distinct classes of action participate; namely, the act of generation by which the germ is produced; and the act of development, by which that germ is evolved into the complete organism." (Carpenter) 2. That from which anything springs; origin; first principle; as, the germ of civil liberty. <biology> Disease germ, the theory that living organisms can be produced only by the evolution or development of living germs or seeds. See Biogenesis, and Abiogenesis. As applied to the origin of disease, the theory claims that the zymotic diseases are due to the rapid development and multiplication of various bacteria, the germs or spores of which are either contained in the organism itself, or transferred through the air or water. See Fermentation theory. Origin: F. Germe, fr. L. Germen, germinis, sprout, but, germ. Cf. Germen, Germane. Source: Websters Dictionary (01 Mar 1998) |
| germ cell | Cell specialised to produce haploid gametes. The germ cell line is often formed very early in embryonic development. (18 Nov 1997) |
| germ cells | The reproductive cells in multicellular organisms. (12 Dec 1998) |
| germ cell tumour | A type of brain tumour. (12 Dec 1998) |
| germ-free animal | An animal which has no microorganisms whatsoever living in or on it. An animal which was born and raised in an isolated environment with no microorganisms in it, such as within a germ-free isolator. (09 Oct 1997) |
| germ-free isolator | A chamber which has absolutely no microorganisms whatsoever living in it, where a germ-free animal can be born and raised. An artificial barrier surrounding a living facility for germ-free animals, which keeps out all microorganisms. (09 Oct 1997) |