| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
|---|---|
| tumour marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| linkage marker | A locus at which there is a high probability of heterozygotes (indispensible state for linkage analysis), but in itself perhaps of no clinical interest. See: marker locus. (05 Mar 2000) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
| genetic carrier | An unaffected heterozygote bearing a usually harmful recessive gene, a cancer that bears a dominant but latent age-dependent trait to have offspring with unbalanced karyotypes. (05 Mar 2000) |
| genetic code | <molecular biology> Relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid. (18 Nov 1997) |
| genetic colonisation | <molecular biology> The process of a parasite (such as a virus) inserting genes into a host's genome which cause the host cell to synthesise products that are only useful to the parasite. (07 May 1998) |
| genetic complement | <biology, genetics> The set of chromosomes contained within any one particular cell. (07 May 1998) |
| genetic complementation | <genetics> The reappearance of wild-type characteristics in a cell or organism that has had two distinct mutations on the same chromosome. Two normal versions of two different mutant genes on different chromosomes affecting the same phenotype which, when inherited together, results in the wild-type phenotype despite the presence of mutant copies of the genes. (09 Oct 1997) |
| genetic complementation test | A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell. (12 Dec 1998) |
| genetic marker |
An identifiable substance that is associated with a normal or an abnormal gene.
출처: www.bdid.com/termsg.htm
|
|---|---|
| genetic marker |
Any gene whose presence can be readily detected by its phenotypic expression and which is used to locate other genes. Also detectable RFLP used to identify a specific linked gene or an individual carrying a gene of interest.
출처: www.knowledgebank.irri.org/glossary/Glossary/G.htm
|
| genetic marker |
an indentifiable segment of DNA that can be mapped to a region of a chromosome.
출처: www.uvm.edu/~cgep/Education/Glossary.html
|
| genetic marker |
A detectable piece of DNA closely linked to a gene of interest whose precise location is unknown. 289
출처: www.mhhe.com/biosci/genbio/life/glossaryg.mhtml
|
| genetic marker |
A gene that is used to identify an individual disease or trait, or trace its inheritance within a family.
출처: www.spondylitis.org/patient_resources/glossary.asp...
|