| GENETOX | Genetic Toxicology [data base] |
|---|---|
| GH | general health; general hospital; genetic hypertension; genetically hypertensive [rat]; geniohyoid; ... |
| GM | gastric mucosa; Geiger-Muller [counter]; general medicine; genetic manipulation; geometric mean; gia... |
| GP | gangliocytic paraganglioma; gastroplasty; general paralysis, general paresis; general practice, gene... |
| GT | gait training; galactosyl transferase; gastrostomy; generation time; genetic therapy; gingiva treatm... |
| equilibrium constant | <chemistry> The ratio of the reverse and forward rate constants for a reaction of the type: A + B = AB at equilibrium the equilibrium constant (K) equals the product of the concentrations of reactants divided by the concentration of product and has dimensions of concentration. Kd = (concentration A.concentration B) / (concentration AB). The affinity constant (Ka) is the reciprocal of the equilibrium constant. Dimension: moles per litre. In general the concept of Kd is more readily understood than that of Ka, for example: in considering the conversion of A to AB by the binding of ligand B, the Kd = B when A = AB. Thus Kd is equal to the ligand concentration which produces half maximal conversion (response). (10 Jan 1998) |
|---|---|
| equilibrium dialysis | In immunology, a method for determination of association constants for hapten-antibody reactions in a system in which the hapten (dialyzable) and antibody (nondialyzable) solutions are separated by semipermeable membranes. Since at equilibrium the quantity of free hapten will be the same in the two compartments, quantitative determinations can be made of hapten-bound antibody, free antibody, and free hapten. (05 Mar 2000) |
| equilibrium potential | <physiology> The membrane potential at which a particular type of ion or other particle does not diffuse through the membrane in either direction. (09 Oct 1997) |
| linkage equilibrium | <genetics> Situation that should exist in a population undisturbed by selection, migration, etc., in which all possible combinations of linked genes should be present at equal frequency. The situation is no more common than are such undisturbed populations. (18 Nov 1997) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
| genetic carrier | An unaffected heterozygote bearing a usually harmful recessive gene, a cancer that bears a dominant but latent age-dependent trait to have offspring with unbalanced karyotypes. (05 Mar 2000) |
| genetic code | <molecular biology> Relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid. (18 Nov 1997) |
| genetic colonisation | <molecular biology> The process of a parasite (such as a virus) inserting genes into a host's genome which cause the host cell to synthesise products that are only useful to the parasite. (07 May 1998) |
| genetic complement | <biology, genetics> The set of chromosomes contained within any one particular cell. (07 May 1998) |
| genetic complementation | <genetics> The reappearance of wild-type characteristics in a cell or organism that has had two distinct mutations on the same chromosome. Two normal versions of two different mutant genes on different chromosomes affecting the same phenotype which, when inherited together, results in the wild-type phenotype despite the presence of mutant copies of the genes. (09 Oct 1997) |