| generalised seizure | <neurology> A type of seizure that results in loss of consciousness, generalised muscle contractions, urinary incontinence, tongue biting and a post-ictal state (confusion and lethargy) following cessation of the seizure. Synonym: grand-mal seizure. See: epilepsy. (03 Jul 1999) |
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| generalised seizures | Seizures characterised by generalised cerebral onset clinically and on EEG. (05 Mar 2000) |
| generalised Shwartzman phenomenon | When both the primary injection of endotoxin-containing filtrate and the secondary injection are given intravenously 24 hours apart, the animal usually dies within 24 hours after the second inoculation; the characteristic lesions in the rabbit include widespread haemorrhages in the lung, liver, and other organs and bilateral cortical necrosis of the kidney. This reaction has no immunological basis. Synonym: Sanarelli phenomenon, Sanarelli-Shwartzman phenomenon. (05 Mar 2000) |
| generalised small bowel disease | <radiology> Hypoproteinaemia, sprue, Whipple (12 Dec 1998) |
| generalised tonic-clonic epilepsy | tonic-clonic seizure |
| generalised tonic-clonic seizure | <neurology> A type of seizure that results in loss of consciousness, generalised muscle contractions, urinary incontinence, tongue biting and a post-ictal state (confusion and lethargy) following cessation of the seizure. Synonym: grand-mal seizure. See: epilepsy. (03 Jul 1999) |
| generalised vaccinia | Secondary lesions of the skin following vaccination which may occur in subjects with previously healthy skin but are more common in the case of traumatised skin, especially in the case of eczema (eczema vaccinatum). In the latter instance, generalised vaccinia may result from mere contact with a vaccinated person. Secondary vaccinial lesions may also occur following transfer of virus from the vaccination to another site by means of the fingers. (05 Mar 2000) |
| persistent generalised lymphadenopathy | A syndrome characterised by reactive hyperplasia of lymph nodes (of at least one month's duration and at two different body sites, not including the inguinal area) in patients infected with the human immunodeficiency virus. The lymph node lesions progress from benign reactive hyperplasia through a stage of mixed follicular hyperplasia, to follicular involution with lymphocyte depletion. Many go on to a malignant non-Hodgkin's lymphoma. (05 Mar 2000) |
| congenital generalised fibromatosis | Multiple subcutaneous and visceral fibrous tumours present at birth; a rare disorder often fatal in the first week of life, although sometimes undergoing spontaneous remission; probable autosomal recessive inheritance. (05 Mar 2000) |
| primary generalised epilepsy | Epilepsy without evidence of focal or multifocal central nervous system disease. Seizures are generalised from onset, both by EEG and clinical criteria. Often a pure genetic form of epilepsy. See: generalised tonic-clonic seizure. (05 Mar 2000) |
| secondarily generalised tonic-clonic seizure | A generalised tonic-clonic seizure that begins with a partial seizure and evolves into a generalised tonic-clonic seizure. (05 Mar 2000) |
| secondary generalised epilepsy | A group of epilepsy syndromes of diverse aetiologies with diffuse or multifocal cerebral involvement. Patients typically have a variety of generalised seizure types, including tonic, atonic, myoclonic, atypical absence, and generalised tonic-clonic seizures. Partial seizures may also occur. One classic syndrome is the Lennox-Gastaut syndrome. Synonym: symptomatic epilepsy. (05 Mar 2000) |
| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
| epilepsy, generalised | Epileptic seizures in which the first clinical changes indicate initial involvement of both hemispheres of the brain, as opposed to epileptic seizures involving a particular focal point of the brain (epilepsy, partial). Generalised seizures can be convulsive or non-convulsive. Consciousness may be impaired and this impairment may be the initial manifestation of the seizure. Motor manifestations, if present, are also bilateral. (12 Dec 1998) |
| acoustic tetanus | Experimental tetanus induced by a faradic current, the speed of which is estimated by the pitch of the vibrations. (05 Mar 2000) |