| GAP syndrome | Galactorrhea, Amenorrhea, Prolactinoma Syndrome |
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| OG | Osmolar Gap; 10 mOsm/kg = measured Osm - calculated Osm |
| VF | 1) Ventricular Fibrillation ? Tx of Ventricular Fibrillation ... |
| AG | abdominal girth; agarose; aminoglutethimide; analytical grade; anion gap; antigen; antiglobulin; ant... |
| B-G | Bordet-Gengou [agar, bacillus, phenomenon] |
| gap mutant | <molecular biology> A fruit fly of the genus Drosophila which is missing a number of adjacent segments because the segments failed to develop. (09 Oct 1997) |
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| GAP protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| chromosomal gap | A localised area of thinning in a chromatid which may simulate a complete break. (05 Mar 2000) |
| silent gap | The period during which Korotkoff sounds indicating true systolic pressure fade away and reappear at a lower pressure point; responsible for errors made in recording falsely low systolic blood pressure, especially in hypertensive patients, of up to 25 mm Hg, and avoided by pumping the cuff 30 mm Hg beyond palpable systolic pressure. Synonym: silent gap. (05 Mar 2000) |
| DNA gap | A localised loss of one of the two strands in the double helix of DNA. (05 Mar 2000) |
| interocclusal gap | The space between the occluding surfaces of the maxillary and mandibular teeth when the mandible is in physiologic resting position. Synonym: interocclusal clearance, interocclusal distance, interocclusal gap, interocclusal rest space. (05 Mar 2000) |
| excitable gap | A short period in the cycle of the atrioventricular or intraventricular conduction allowing passage of an impulse which at other times would be blocked in transit. Synonym: excitable gap. (05 Mar 2000) |
| adhesion phenomenon | A phenomenon manifested by the adherence of antigen-antibody-complement complex to "indicator cells" (microorganisms, platelets, leukocytes, or erythrocytes), the reaction being sensitive and specific for the antigen and antibody in the complex. Synonym: erythrocyte adherence phenomenon, immune adherence phenomenon, red cell adherence phenomenon. (05 Mar 2000) |
| AFORMED phenomenon | As induced pulsus alternans progresses, a state in which alternating heart depolarisations fail to eject any blood, thus allowing longer diastolic filling; the subsequent beat is then able to produce a significant ejection; at high rates the cardiac minute volume and blood pressure may appear normal. Origin: Alternating, failure of response, mechanical, to electrical depolarisation (05 Mar 2000) |
| all-or-nothing phenomenon | <physiology> Refers to the phenomenon where the strength of a nerve impulse is not dependent on the strength of the stimulus. Instead, there is a threshold level of stimulus strength that must be reached before the nerve will fire an impulse (at full capacity). Below the threshold, the nerve will not fire at all. <cardiology> It also refers to the same phenomenon observed in the heart muscle, which will either contract fully or not at all. <psychology> In studies of behaviour, it refers to the same phenomenon where a behavioural stimulus will either produce a complete response or no response at all. Also called all-or-nothing principle, all-or-none law, all-or-none responsiveness, etc. (15 Nov 1997) |
| Anrep phenomenon | Homeometric autoregulation of the heart whereby cardiac performance improves as the afterload (aortic pressure) is increased. (05 Mar 2000) |
| aqueous influx phenomenon | The filling of the aqueous vein, which normally carries blood and aqueous, with aqueous, when the junction of the aqueous vein and the recipient vein is partially occluded. Synonym: Ascher's aqueous influx phenomenon. (05 Mar 2000) |
| Arias-Stella phenomenon | Focal, unusual, decidual changes in endometrial epithelium, consisting of intraluminal budding, and nuclear enlargement and hyperchromatism with cytoplasmic swelling and vacuolation; may be associated with ectopic or uterine pregnancy. Synonym: Arias-Stella effect, Arias-Stella reaction. (05 Mar 2000) |
| arm phenomenon | In tetany, spasm both of the extensor muscles of the knee and of the calf muscles when the extended leg is flexed at the hip. Synonym: leg phenomenon, Pool-Schlesinger sign, Schlesinger's sign. In tetany, contraction of the arm muscles following the stretching of the brachial plexus by elevation of the arm above the head with the forearm extended, resembles the contraction resulting from stimulation of the ulnar nerve. Synonym: arm phenomenon. (05 Mar 2000) |
| Arthus phenomenon | A form of immediate hypersensitivity resulting in erythema, oedema, haemorrhage, and necrosis observed in rabbits after injection of antigen to which the animal has already been sensitised and has specific IgG antibodies. The reaction is caused by the inflammation that results from the deposition of antigen-antibody complexes in tissue spaces and in blood vessel walls that activate complement, most of the damage seemingly being due to the polymorphonuclear leukocytes that phagocytise the deposits and release lysosomal enzymes. The phenomenon, described by Arthus, was in rabbits, but similar reactions (Arthus-type reactions) are observed in guinea pigs, rats, and dogs, as well as in humans. See: Arthus reaction. Synonym: Arthus reaction. (05 Mar 2000) |