| fungal infection | 1. (groin) Tinea cruris is a fungal infection of the perineum, better known as jock itch. This condition is often treated with clotrimazole or miconazole cream. Good general hygiene is vital in the prevention of tinea cruris. Keep the groin area clean and dry and avoid chafing. Launder athletic supporters frequently. Use an antifungal or drying powder after showering. 2. (nail) A fungal infection that involves the fingernails. Nails generally split, flake and grow too thick. 3. (scalp): A fungal scalp infection also known as tinea capitis. A crusting and scaly lesion of the scalp that can also be associated with localised hair loss. Treatment requires oral (systemic) antifungal medications. (05 Jan 1998) |
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| fungal nail infection | The most common fungus infection of the nail is onychomycosis. Onychomycosis makes the nails look white and opaque, thickened, and brittle. Older women (perhaps because oestrogen deficiency may increase the risk of infection) and men and women with diabetes or disease of the small blood vessels (peripheral vacscular disease) are at increased risk. Artificial nails (acrylic or wraps ) increase the risk because when an artificial nail is applied, the nail surface is usually abraded with an emery board damaging it, emery boards can carry infection, and water can collect under the nail creating a moist, warm environment for fungal growth. Alternative names include tinea unguium and ringworm of the nails. (12 Dec 1998) |
| fungal proteins | Proteins found in any species of fungus. (12 Dec 1998) |
| fungal vaginitis | <pathology> A local infection of the vaginal mucosa caused by Candida. (27 Sep 1997) |
| aids vaccines | Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent aids. Some vaccines containing antigens are recombinantly produced. (12 Dec 1998) |
| bacterial vaccines | Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease. (12 Dec 1998) |
| cancer vaccines | Vaccines or candidate vaccines designed to prevent or treat cancer. Vaccines are produced using the patient's own whole tumour cells as the source of antigens, or using tumour-specific antigens, often recombinantly produced. (12 Dec 1998) |
| vaccines | Vaccines are microbial preparations of killed or modified microorganisms which can stimulate an immune response in the body in order to prevent future infection with similar microorganism. The smallpox vaccine has totally eliminated the smallpox disease from our planet. (12 Dec 1998) |
| vaccines, attenuated | Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. (12 Dec 1998) |
| vaccines, combined | Two or more vaccines in a single dosage form. (12 Dec 1998) |
| vaccines, conjugate | Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognised by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection. (12 Dec 1998) |
| vaccines, DNA | Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. (12 Dec 1998) |
| vaccines, inactivated | Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins. (12 Dec 1998) |
| vaccines, synthetic | Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. (12 Dec 1998) |
| malaria vaccines | Vaccines made from antigens arising from any of the four strains of plasmodium which cause malaria in humans, or from p. Berghei which causes malaria in rodents. (12 Dec 1998) |