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delta 14-sterol reductase <enzyme> Reduces ignosterol to ergosterol; NADPH-dependent enzyme that catalyses the formal trans addition of hydrogen across the 14,15-pi bond in 8,14-sterol dienes; forms 4,4-dimethylzymosterol in lanosterol metabolism pathway from 4,4-dimethyl-5alpha-cholesta-8,14,25-trien-3beta-ol or from 4,4-dimethyl-cholesta-8,14,24-trienol; erg24 from saccharomyces cerevisiae
Registry number: EC 1.3.1.-
Synonym: ignosterol reductase, delta 8,14-sterol delta 14-reductase, 14,15-sterol reductase, delta 8,14-steroid 14-reductase, delta 14,15-reductase, sterol c-14 reductase, c-14 sterol reductase, erg24 gene product
(26 Jun 1999)
delta-22 sterol desaturase <enzyme> Catalyses the formation of the sterol side delta-22-double bond from 23-hydroxysterols
Registry number: EC 1.3.3.-
Synonym: c-22 sterol desaturase, cyp61, cytochrome p-45061, sterol delta22-desaturase
(26 Jun 1999)
delta 24-sterol methyltransferase <enzyme> Substrate sterols may be replaced by specific sterol
Registry number: EC 2.1.1.41
Synonym: s-adenosylmethionine zymosterol methyltransferase, s-adenosylmethionine-delta 24-sterol-c-methyltransferase, sterol c-24 s-adenosylmethionine methyltransferase, sed6 protein, erg6 protein, (s)-adenosyl-l-methionine-delta 24(25)-sterol methyltransferase
(26 Jun 1999)
delta 5,7-sterol delta-7-reductase <enzyme> Involved in cholesterol biosynthesis, introduces the delta-5 bond into delta 7-cholestenol to form 7-dehydrocholesterol
Registry number: EC 1.3.1.-
Synonym: delta 7-sterol reductase, delta 7-sterol desaturase, delta 7-sterol 5-desaturase
(26 Jun 1999)
delta(8)-delta(7)-sterol isomerase <enzyme> Catalyses anaerobic conversion of sterol-8-ene to sterol-7-ene; do not confuse with erg-2 protein from retroviridae
Registry number: EC 5.3.3.-
Synonym: delta 8 - delta 7 sterol isomerase, c-8 sterol isomerase, erg2 gene product, fungal, sterol 8-isomerase
(26 Jun 1999)
4-methyl sterol demethylase <chemical> This term is used to describe 10 reactions in the collective processes of monooxygenation, decarboxylation and reduction, which, together account for the conversion of each of the two 4-methyl groups of lanosterol to carbon dioxide
Chemical name: demethylase, methyl sterol
Synonym: 4,4-dimethylzymosterol monooxygenase, sterol 4-demethylase
(26 Jun 1999)
acetaldehyde oxidase <enzyme> Acetaldehyde is converted to acetate
Registry number: EC 1.2.-
(26 Jun 1999)
acyl-CoA oxidase <enzyme> Catalyses stoichiometric conversion of palmitoyl-CoA and o2 into 2-hexadecenoyl-CoA and h2o2; oxidises acyl-CoA's with carbon chain lengths of 4 to 20; most active toward lauroyl-CoA, but not acetyl- or succinyl-CoA
Registry number: EC 1.3.3.6
Synonym: fatty acyl CoA oxidase, fatty acyl-coenzyme a oxidase, fatty acid acyl-CoA oxidase, acox, pox1 gene product
(26 Jun 1999)
adrenaline oxidase amine oxidase (flavin-containing)
aldehyde oxidase <enzyme> Broad substrate specificity
Registry number: EC 1.2.3.1
Synonym: n1-methylnicotinamide oxidase I, n-nitrosoreductase
(26 Jun 1999)
alternative oxidase <enzyme> The terminal oxidase in alternative pathway respiration, as seen in plants like sauromatum guttatum (voodoo lily); amino acid sequence for tobacco alternative oxidase (aox1) in first source
Registry number: EC 1.-
Synonym: aox1 gene product, aox2 gene product, aox3 gene product
(26 Jun 1999)
alternative oxidase pathway Pathway of mitochondrial electron transport in higher plants, particularly in fruits and seeds, that does not involve cytochrome oxidase and thus is resistant to cyanide.
(18 Nov 1997)
amine oxidase <enzyme> A group of enzymes including those oxidizing primary monoamines, diamines, and histamine.
They are copper proteins, and, as their action depends on a carbonyl group, they are sensitive to inhibition by saemicarbazide.
Chemical name: Amine:oxygen oxidoreductase (deaminating)(copper-containing)
Registry number: EC 1.4.3.6
(12 Dec 1998)
amine oxidase (copper-containing) An oxidoreductase containing copper, and perhaps pyridoxal phosphate, and carrying out the same reaction as amine oxidase (flavin-containing).
Synonym: amine oxidase (pyridoxal-containing), diamine oxidase, diamino oxyhydrase, histaminase.
(05 Mar 2000)
amine oxidase (flavin-containing) An oxidoreductase containing flavin and oxidizing amines with the aid of O2 and water to aldehydes or ketones with the release of NH3 and H2O2. Acted upon by antidepressants.
Synonym: adrenaline oxidase, diamine oxidase, monoamine oxidase, tyraminase, tyramine oxidase.
(05 Mar 2000)
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