| fluorescent antibody technique, direct | A form of fluorescent antibody technique utilizing a fluorochrome conjugated to an antibody, which is added directly to a tissue or cell suspension for the detection of a specific antigen. (12 Dec 1998) |
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| fluorescent antibody technique, indirect | A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labelled with fluorescein-conjugated anti-immunoglobulin antibody. (12 Dec 1998) |
| fluorescent antibody techniques | Lab techniques for locating antigens in a prepared tissue sample by using antibodies with fluorescent labels which will bind to the antigens of interest. (09 Oct 1997) |
| fluorescent antibody titre | An indirect method of measuring the concentration of an antibody in serum through the detection of fluorescent light emitted in a chemical reaction. (27 Sep 1997) |
| fluorescent dyes | Dyes that emit light when exposed to light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. They are used as markers in biochemistry and immunology. (12 Dec 1998) |
| fluorescent in situ hybridization | See FISH. (12 Dec 1998) |
| fluorescent label | A molecule which fluoresces and can be attached to a probe molecule that does not fluoresce. (09 Oct 1997) |
| fluorescent microscope | <instrument> A microscope equipped to examine material that fluoresces under ultraviolet (UV) light. (12 Dec 1998) |
| fluorescent screen | A screen coated with fluorescent crystals such as the calcium tungstate used in the fluoroscope. (05 Mar 2000) |
| fluorescent stain | <technique> A stain or staining procedure using a fluorescent dye or substance that will combine selectively with certain tissue components and that will then fluoresce upon irradiation with ultraviolet or violet-blue light. (05 Mar 2000) |
| age spot | <dermatology> A skin disorder seen with aging (or sun exposure) where there are flat patches of increased pigmentation on the skin. They are nonserious, benign and generally more important cosmetically. The most commonly appear on sun exposed areas such as the forehead and the back of the hands. Avoidance of the sun and the use of a sunscreen (SPF of 15) can reduce the incidence of these lesions. Creams and lotions are available which bleach the skin. Cryotherapy can be used in some cases. (27 Sep 1997) |
| blind spot | The negative scotoma in the visual field, corresponding to the optic disk. Synonym: blind spot. (05 Mar 2000) |
| blue spot | A bluish stain on the skin caused by the bites of fleas or lice, especially pediculosis pubis. Synonym: blue spot, tache bleuatre. (05 Mar 2000) |
| cafe-au-lait spot | <dermatology> A pigmented cutaneous lesion, that can range from light to dark brown, and is due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes. Caf |
| Mariotte's blind spot | The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve. Because the retina at the optic disk has no photoreceptors there is a corresponding blind spot in the visual field. (12 Dec 1998) |