| flat wart | A smooth, flat, flesh-coloured wart of small size, occurring in groups, seen especially on the face of the young; often associated with common warts of the hands, due to human papilloma virus, commonly, types 3 and 10. Synonym: flat wart, plane wart, verruca plana juvenilis. (05 Mar 2000) |
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| acute vascular purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| allergic purpura | Nonthrombocytopenic purpura due to sensitization to foods, drugs, and insect bites. Synonym: anaphylactoid purpura. (05 Mar 2000) |
| anaphylactoid purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| autoimmune thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| Waldenstrom's purpura | <haematology> A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen. (27 Sep 1997) |
| Henoch-Schonlein purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| Henoch's purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| Schonlein's purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| psychogenic purpura | <syndrome> A condition, usually occurring in women, in which the individual bruises easily (purpura simplex) and the ecchymoses tend to enlarge and involve adjacent tissues, resulting in pain in the affected parts; so-called because similar lesions are produced by inoculation of the individual's blood or various components of red blood cells and it is thought to be a form of localised autosensitization, although no specific antibodies have been demonstrable; in some individuals, there seems to be a psychogenic mechanism. Synonym: Gardner-Diamond syndrome, psychogenic purpura. (05 Mar 2000) |
| purpura | <clinical sign, dermatology> A small haemorrhage (up to about 1 cm in diameter) in the skin, mucous membrane or serosal surface, which may be caused by various factors, including blood disorders, vascular abnormalities and trauma. Purpuric lesions may be associated with inflammation, in which case they present as papular purpura or the haemorrhage may not be accompanied by inflammation, in which case they are macular. The term also comprises a group of haemorrhagic diseases characterised by the presence of purpuric lesions, ecchymoses and a tendency to bruise easily, which may be caused by decreased platelet counts, the presence of abnormal platelets, vascular defects or reactions to certain drugs. (15 Dec 1997) |
| purpura, anaphylactoid | See Purpura, Henoch-Schonlein. (12 Dec 1998) |
| purpura angioneurotica | An eruption marked by angioneurotic oedema, petechiae, and hyperesthesia of the skin and gastric mucous membrane. (05 Mar 2000) |
| purpura annularis telangiectodes | Asymptomatic annular lesions, principally of the lower extremities of adolescent males, in which the peripheral portion is composed of purpura or petechiae with brawny staining of haemosiderin deposits and minute telangiectasia. Synonym: Majocchi's disease. (05 Mar 2000) |
| purpura fulminans | A severe and rapidly fatal form of purpura haemorrhagica, occurring especially in children, with hypotension, fever, and disseminated intravascular coagulation, usually following an infectious illness. (05 Mar 2000) |