| cell transformation, neoplastic | Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. (12 Dec 1998) |
|---|---|
| cell transformation, viral | An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. (12 Dec 1998) |
| centrifugal fast analyzer | An automatic spectrophotometer that uses centrifugal force to mix samples and reagents, and propels the reactants at high speed about a detector that makes multiple absorbance readings. (05 Mar 2000) |
| Wassermann-fast | A term used to designate a case in which the Wassermann reaction remains positive despite all treatment. (05 Mar 2000) |
| Haldane transformation | The multiplication of inspired oxygen concentration by the ratio of expired to inspired nitrogen concentrations in the calculation of oxygen consumption or respiratory quotient by the open circuit method. (05 Mar 2000) |
| histamine-fast | Indicating the absence of the normal response to histamine, especially in speaking of true gastric anacidity. (05 Mar 2000) |
| serum-fast | 1. Pertaining to a serum in which there is little or no change in the titre of antibody, even under conditions of treatment or immunologic stimulation. 2. Resistant to the destructive effect of sera. Synonym: serofast. (05 Mar 2000) |
| sol gel transformation | Transition between more fluid cytoplasm (endoplasm) and stiffer gel like ectoplasm proposed as a mechanism for amoeboid locomotion: since the endoplasm cannot really be considered a simple fluid and has visco elastic properties like a gel, the term is misleading. (18 Nov 1997) |
| spectrometry, mass, fast atom bombardment | A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information. (12 Dec 1998) |
| spontaneous transformation | Transformation of a cultured cell that occurs without the deliberate addition of a transforming agent. Cells from some species, especially rodents, are particularly prone to such spontaneous transformation. (18 Nov 1997) |
| sputum for acid-fast organisms | A special microscopic slide that is prepared to detect the presence of acid-fast bacilli. The diagnosis of tuberculosis can be made using this test. If the sputum specimen shows the acid fast organism a sputum culture (for Mycobacterium) is then performed. (27 Sep 1997) |
| nodular transformation of the liver | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| drug-fast | Pertaining to microorganisms that resist or become tolerant to an antibacterial agent. (05 Mar 2000) |
| iodine-fast | Denoting hyperthyroidism unresponsive to iodine therapy, which develops frequently in most cases so treated. (05 Mar 2000) |
| transformation | <chemistry> The change of form or structure, conversion from one form to another. <oncology> The change that a normal cell undergoes as it becomes malignant. In eukaryotes, the conversion of normal cells to malignant cells in cell culture. Origin: L. Formatio = formation (18 Nov 1997) |