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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 2
  • Factor XIa - »õâ Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium.
    Synonyms : Activated Factor XI, Blood Coagulation Factor XI, Activated, Contact Activation Product, Factor XIa, Coagulation, XIa, Coagulation Factor
  • Factor XII - »õâ Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease.
    Synonyms : Blood Coagulation FactorXI, Coagulation FactorXI, Blood, Factor XII, Coagulation, FactorXI, Blood Coagulation, XII, Coagulation Factor
  • Factor XII Deficiency - »õâ An absence or reduced level of blood coagulation factor XII. It normally occurs in the absence of patient or family history of hemorrhagic disorders and is marked by prolonged clotting time.
    Synonyms : Deficiency, Factor XII, Deficiencies, Factor XII, Factor XII Deficiencies, Trait, Hageman
  • Factor XIIa - »õâ Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.
    Synonyms : Activated Factor XII, Blood Coagulation Factor XII, Activated, Hageman-Factor Fragments, Prekallikrein Activator, Activator, Prekallikrein, Factor XIIa, Coagulation, Fragments, Hageman-Factor, Hageman Factor Fragments, XIIa, Coagulation Factor
  • Factor XIII - »õâ A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.
    Synonyms : Blood Coagulation Factor XIII, Factor XIII A-Chain, Laki Lorand Factor, Factor XIII A Chain, Factor XIII, Coagulation, Stabilizing Factor, Fibrin, Transamidase, Factor XIII, XIII, Coagulation Factor
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 2
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