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extrinsic pathway <haematology> Initiation of blood clotting as a result of factors released from damaged tissue, as opposed to contact with a foreign surface (the intrinsic pathway).
Tissue thromboplastin (Factor III) in conjunction with Factor VII proconvertin) will activate Factor X that, once activated, converts prothrombin to thrombin.
(27 Jun 1999)
extrinsic protein <protein> A protein found in a cell or tissue which came from somewhere else (other than the cell or tissue in which it is found).
(09 Oct 1997)
extrinsic proteins Pathways that can be easily removed from a biomembrane (e.g., by altering the pH or the ionic strength).
Synonym: extrinsic proteins.
(05 Mar 2000)
extrinsic sphincter A sphincter provided by circular muscular fibres extraneous to the organ.
(05 Mar 2000)
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