| pertussis toxin | <protein> Protein complex (ca 117 kD). An A B toxin, the active subunit is a single polypeptide 28 kD), the binding subunit a pentamer (two heterodimers, 23 + 11.7 kD, 11.7 + 22 kD and a monomer (9.3 kD) that binds the heterodimers). The active subunit ADP ribosylates the _ subunit of the inhibitory GTP-binding protein (Gi). Crucial to the pathogenicity of Bordetella pertussis, the causative agent of whooping cough. (18 Nov 1997) |
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| cholera toxin | <protein> A multimeric protein toxin from Cholera vibrio. The toxic A subunit activates adenyl cyclase irreversibly by ADP ribosylation of a Gs protein. The B subunit facilitates passage of the A subunit across the cell membrane. (18 Nov 1997) |
| cholera toxin, B subunit-horseradish peroxidase | <chemical> Conjugate of horseradish peroxidase and cholera toxin Synonym: bhrp, horseradish peroxidase-cholera toxin b subunit, cholera toxin-horseradish peroxidase, horseradish peroxidase-cholera toxin, ib4-hrp (26 Jun 1999) |
| cobra toxin | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| plant toxin | A substance similar in its properties to an extracellular bacterial toxin. Synonym: plant toxin. Origin: phyto-+ G. Toxikon, poison (05 Mar 2000) |
| Crotalus toxin | <herpetology> The toxin of rattlesnake. (05 Mar 2000) |
| HC toxin reductase | <enzyme> Nadph-dependent enzyme from maise which inactivates the cyclic tetrapeptide, hc toxin, from cochliobolus carbonum; amino acid sequence given in first source Registry number: EC 1.- Synonym: hm1 gene product (26 Jun 1999) |
| scarlet fever erythrogenic toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |
| Schick test toxin | Corynebacterium diphtheriae toxin diluted so that the inoculated dose (0.1 or 0.2 ml) will contain 1/50 th of guinea pig minimal lethal dose. See: Schick test. Synonym: diagnostic diphtheria toxin. (05 Mar 2000) |
| Shiga like toxin | <protein> Group of structurally related toxins that block eukaryotic protein synthesis by cleaving the 28S rRNA subunit of ribosomes. Examples: Shiga toxin, Shiga like toxins SLT 1 and SLT 2 of Escherichia coli. (18 Nov 1997) |
| Shiga toxin | <protein> Bacterial toxin from Shigella dysenteriae that blocks eukaryotic protein synthesis. See: Shiga like toxins. (18 Nov 1997) |
| streptococcus erythrogenic toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |
| normal toxin | A toxin solution holding exactly 100 lethal doses in 1 ml. (05 Mar 2000) |
| diagnostic diphtheria toxin | Corynebacterium diphtheriae toxin diluted so that the inoculated dose (0.1 or 0.2 ml) will contain 1/50 th of guinea pig minimal lethal dose. See: Schick test. Synonym: diagnostic diphtheria toxin. (05 Mar 2000) |
| Dick test toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |