| hypothesis | <statistics> A supposition that appears to explain a group of phenomena and is advanced as a basis for further investigation, a proposition that is subject to proof or to an experimental or statistical test. (11 Jan 1998) |
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| sliding filament hypothesis | The theory that the contracting muscle shortens because two sets of filaments slide past each other. (05 Mar 2000) |
| Starling's hypothesis | The principle that net filtration through capillary membranes is proportional to the transmembrane hydrostatic pressure difference minus the transmembrane oncotic pressure difference; although well established, it is called Starling's hypothesis to distinguish it from Starling's law of the heart. (05 Mar 2000) |
| Neyman-Pearson statistical hypothesis | A formal conjecture about the numerical value of a parameter to be tested exclusively in the light of an immediate set of data without attention to prior knowledge or convictions and ignoring other sets of evidence treated in a similar fashion. The answer is a statement not about whether the hypothesis is true but whether it is an acceptable explanation of the data or should be rejected in favour of another hypothesis. (05 Mar 2000) |
| null hypothesis | The assumption that any observed difference between two samples of a statistical population is purely accidental and not due to systematic causes. (05 Dec 1998) |
| dual recognition hypothesis | An outmoded hypothesis that is known to be incorrect now that the structure of the T-cell receptor is known. The proposal was that viral (and some chemical) antigens were recognised in association with histocompatibility antigens by separate receptors on the T-cell. The generation of cytotoxic T-cells was by association with Class I MHC antigens, of T helper cells by association with Class II MHC antigens. See: altered self hypothesis. (18 Nov 1997) |
| insular hypothesis | An obsolete theory of the origin of diabetes mellitus from destruction or loss of function of the islets of Langerhans in the pancreas. (05 Mar 2000) |
| uniform rate hypothesis | <biology> This states that any two evolving organismal lineages diverge from a common ancestor at a constant rate with respect to each other. (09 Oct 1997) |
| unineme hypothesis | <cell biology, molecular biology> This states that that a chromatid has only one DNA duplex, which goes from one end of the chromatid to the other. (09 Oct 1997) |
| zwitter hypothesis | That an amphoteric molecule (e.g., an amino acid) has, at its isoelectric point, equal numbers of positive and negative charges, thus becoming a zwitterion. (05 Mar 2000) |
| frustration-aggression hypothesis | The theory that frustration may lead to aggression, but that aggression is always the result of some form of frustration. (05 Mar 2000) |
| Lyon hypothesis | <genetics> Hypothesis, first advanced by Lyon, concerning the random inactivation of one of the two X chromosomes of the cells of female mammals. In consequence females are chimaeric for the products of the X chromosomes, a situation that has been exploited in female Negroes (who are heterotypic for isozymes of glucose 6 phosphate dehydrogenase) as a means to confirm the monoclonal origin of papillomas and of atherosclerotic plaques. (20 Mar 1998) |
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