| DABP | D site albumin promoter binding protein |
|---|---|
| E* | lesion on the erythrocyte cell membrane at the site of complement fixation |
| FMR | fragile site mental retardation [syndrome]; Friend-Moloney-Rauscher [antigen] |
| fra | fragil [site] |
| FRAXE | X-linked mental retardation-fragile site [syndrome] |
| protein splicing | Excision of in-frame internal protein sequences (inteins) of a precursor protein, coupled with ligation of the flanking sequences (exteins). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein. (12 Dec 1998) |
|---|---|
| self splicing | <molecular biology> Self catalysed removal of group 5 introns, mediated by six paired conserved regions. (18 Nov 1997) |
| splicing | <molecular biology> The process by which introns are removed from hnRNA to produce mature messenger RNA that contains only exons. Alternative splicing seems to occur in many proteins and by alternative exon usage a set of related proteins can be generated from one gene, often in a tissue or developmental stage specific manner. (18 Nov 1997) |
| splicing endonuclease | <enzyme> Cleaves intervening sequences of precursors trna, which are then joined by an RNA ligase Registry number: EC 3.1.27.- Synonym: pre-trna splicing endonuclease, trna splicing endonuclease, splicing endonuclease (xenopus), 3'-pre-trna endonuclease, trna-splicing endonuclease (26 Jun 1999) |
| intron splicing | The excision of mRNA fragments, which correspond to non-coding DNA introns, and the ligation of the remaining mRNA fragments to form a single molecule. (14 Nov 1997) |
| trans splicing | <molecular biology> Relating to RNA splicing of two different pre mRNA molecules together. Seems to rely on intron like sequences. Contrasts with the normal cis splicing of conventional RNA molecules. (19 Jan 1998) |
| trans-splicing | Formation of spliced products containing portions of two different transcripts. (05 Mar 2000) |
| tRNA splicing ligase | <enzyme> One of two enzymes involved in trna splicing in archaea Registry number: EC 6.5.1.- (26 Jun 1999) |
| acceptor site | The ribosomal binding site for the aminoacyl-tRNA during protein synthesis. (05 Mar 2000) |
| active site | <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site). (06 May 1997) |
| allosteric site | A specific site on a multi-subunit enzyme or other protein that is not the substrate binding site, but that when reversibly bound by an effector, induces a conformational change in the protein, altering its catalytic or binding properties. (12 Dec 1998) |
| amidation site | <molecular biology> A C terminus consensus sequence, required for C terminus amidation of peptides. Consensus is glycine, followed by 2 basic amino acids (arg or lys). (18 Nov 1997) |
| antibody combining site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-binding site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-combining site | See: paratope. (05 Mar 2000) |