| CDLE | chronic discoid lupus erythematosus |
|---|---|
| DIL, Dil | Dilantin; drug-induced lupus [erythematosus] |
| DILE | drug-induced lupus erythematosus |
| LE | lactate extraction; left ear; left eye; leukocyte elastase; leukoerythrogenic; live embryo; Long Eva... |
| LED | light-emitting diode; lowest emitting dose; lupus erythematosus disseminatus |
| acute disseminated myositis | The occurrence of multiple foci of acute inflammation in the muscular tissue and overlying skin in various parts of the body, accompanied by fever and other signs of systemic infection. See: dermatomyositis. Synonym: acute disseminated myositis, pseudotrichinosis, pseudotrichiniasis. (05 Mar 2000) |
|---|---|
| disseminated | Scattered, distributed over a considerable area. (16 Dec 1997) |
| disseminated choroiditis | Chronic inflammation of the choroid, with multiple isolated foci. (05 Mar 2000) |
| disseminated cutaneous gangrene | A bullous or pustular eruption, of uncertain origin, followed by necrotic ulcers or extensive gangrene in children under 2 years of age; if untreated, death may result from haematogenous infection, such as liver abscess. Synonym: disseminated cutaneous gangrene, ecthyma gangrenosum, pemphigus gangrenosus, rupia escharotica. (05 Mar 2000) |
| disseminated cutaneous leishmaniasis | Leishmaniasis caused by several New and Old World species and strains of Leishmania (L. Mexicana amazonensis, L. M. Pifanoi, possibly L. M. Garnhami and L. M. Venezuelensis; in Ethiopia, L. Aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the non-ulcerating, non-necrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not appear to occur unless an acquired cellular hypersensitivity can develop. Synonym: anergic leishmaniasis, diffuse leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa, pseudolepromatous leishmaniasis. (05 Mar 2000) |
| disseminated disease | Disease in which the cancerous cells have spread from the tissue of origin to other organs. (13 Nov 1997) |
| disseminated gonococcal infection | Infection from Neisseria gonorrhoea which is spread to distant parts of the body beyond the original portal of entry (usually the lower genital tract). Usually manifest by rash and arthritis. (05 Mar 2000) |
| disseminated intravascular coagulation | <haematology> Complication of septic shock in which endotoxin (from gram-negative bacteria) induces systemic clotting of the blood, probably indirectly through the effect of endotoxin on neutrophils. It may also develop in other situations where neutrophils become systemically hyperactivated. Acronym: DIC (11 Jan 1998) |
| disseminated necrotizing leukoencephalopathy | <radiology> DNL: demyelination due to radiation and chemotherapy, decreased density in deep white matter, with or without peripheral, patchy enhancement, calcification: basal ganglia, grey/white junction (12 Dec 1998) |
| disseminated sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
| disseminated tuberculosis | <microbiology> Usually a chronic tuberculosis infection where spread of the original primary infection has occurred via the patients lymphatic system (or bloodstream). Disseminated disease occurs primarily in the immunocompromised individual (for example AIDS, cancer patient). The elderly are at increased risk for dissemination. In disseminated disease, organs and tissues that can be affected include pericardium, peritoneum, larynx, bronchus, bone, joints, lymph nodes, stomach, meninges, eyes, kidneys and skin. Treatment is with INH, rifampin, ethambutol and other antibiotics. (11 Jan 1998) |
| encephalomyelitis, acute disseminated | An acute or subacute encephalomyelitis or myelitis characterised by perivascular lymphocyte and mononuclear cell infiltration and demyelination. It occurs most commonly following an acute viral infection, especially measles, but may occur without a recognizable antecedent, and formerly occurred as a complication of rabies and smallpox vaccination. (12 Dec 1998) |
| pemphigus erythematosus | An eruption involving sun-exposed skin, especially the face; the lesions are scaling erythematous macules and blebs, combining the clinical features of both lupus erythematosus and pemphigus vulgaris; bullae are subcorneal; probably a variant of pemphigus foliaceus. Synonym: Senear-Usher disease, Senear-Usher syndrome. (05 Mar 2000) |
| chilblain lupus | Skin lesions seen in patients with lupus erythematosus, resembling the small, hardened nodular areas of a cold injury called chilblains. Synonym: chilblain lupus. (05 Mar 2000) |
| neonatal lupus | Lupus erythematosus occurring in newborn children of mothers who had lupus during pregnancy; anti-SSA antibodies usually should be screened for; 50% have anti-nuclear antibodies. A variety of skin lesions are seen, which can resolve or leave scarring; the syndrome usually resolves; however cardiac manifestations can be fatal. Some children develop systemic lupus later in life. (05 Mar 2000) |