| IVBC | intravascular blood coagulation |
|---|---|
| IVC | inferior vena cava; inspiratory vital capacity; integrated vector control; intravascular coagulation... |
| LIC | left internal carotid [artery]; limiting isorrheic concentration; local intravascular coagulation |
| CCF | cancer coagulation factor; cardiolipin complement fixation; carotid-cavernous fistula; centrifuged c... |
| coag | coagulation, coagulated |
| disseminated sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
|---|---|
| disseminated tuberculosis | <microbiology> Usually a chronic tuberculosis infection where spread of the original primary infection has occurred via the patients lymphatic system (or bloodstream). Disseminated disease occurs primarily in the immunocompromised individual (for example AIDS, cancer patient). The elderly are at increased risk for dissemination. In disseminated disease, organs and tissues that can be affected include pericardium, peritoneum, larynx, bronchus, bone, joints, lymph nodes, stomach, meninges, eyes, kidneys and skin. Treatment is with INH, rifampin, ethambutol and other antibiotics. (11 Jan 1998) |
| encephalomyelitis, acute disseminated | An acute or subacute encephalomyelitis or myelitis characterised by perivascular lymphocyte and mononuclear cell infiltration and demyelination. It occurs most commonly following an acute viral infection, especially measles, but may occur without a recognizable antecedent, and formerly occurred as a complication of rabies and smallpox vaccination. (12 Dec 1998) |
| blood coagulation | The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. (12 Dec 1998) |
| blood coagulation factor inhibitors | Substances, usually endogenous, that act as inhibitors of blood coagulation. They may affect one or multiple enzymes throughout the process. As a group, they also inhibit enzymes involved in processes other than blood coagulation, such as those from the complement system, fibrinolytic enzyme system, blood cells, and bacteria. (12 Dec 1998) |
| blood coagulation factors | Endogenous substances, usually proteins, that participate in the blood coagulation process. (12 Dec 1998) |
| blood coagulation tests | Laboratory tests for evaluating the individual's clotting mechanism. (12 Dec 1998) |
| coagulation | 1. <haematology> The process of clot formation. 2. <chemistry> The solidification of a sol into a gelatinous mass, an alteration of a disperse phase or of a dissolved solid which causes the separation of the system into a liquid phase and an insoluble mass called the clot or curd. Coagulation is usually irreversible. 3. <surgery> The disruption of tissue by physical means to form an amorphous residuum, as in electrocoagulation and photocoagulation. Origin: L. Coagulatio (18 Nov 1997) |
| coagulation factor | <haematology> Group of plasma protein substances (Factor I-XIII) contained in the plasma, which act in concert to bring about blood coagulation. Many of the factors contain EGF like domains. (29 Sep 1997) |
| coagulation factor XI | <haematology> A plasma serine protease with an apple domain. (18 Nov 1997) |
| coagulation necrosis | A type of necrosis in which the affected cells or tissue are converted into a dry, dull, fairly homogeneous eosinophilic mass without nuclear staining, as a result of the coagulation of protein as occurs in an infarct; microscopically, the necrotic process involves chiefly the cells, and remnants of histologic elements (e.g., elastin, collagen, muscle fibres) may be recognizable, as well as "ghosts" of cells and portions of cell membranes; may be caused by heat, ischemia, and other agents that destroy tissue, including enzymes that would continue to alter the devitalised cellular substance. (05 Mar 2000) |
| coagulation profile | A test which measures the speed of blood coagulation at different steps of the coagulation pathway. (27 Sep 1997) |
| coagulation time | The time required for blood to coagulate; prolonged in haemophilia and in the presence of obstructive jaundice, some anaemias and leukaemias, and some of the infectious diseases. Synonym: clotting time. (05 Mar 2000) |
| coagulation vitamin | An obsolete term for vitamin K. (05 Mar 2000) |
| whole blood coagulation time | Measurement of the time required by whole blood to produce a visible clot. Factors that could influence the test are all but III, vii, and xiii. Activation may be by contact with the glass tube or exposure to diatomaceous earth. Delay of onset of coagulation may be achieved by use of nonwettable plastic or silicone-coated glass tubes. It is used for monitoring heparin therapy and as a bedside screening test for deficiencies in the intrinsic coagulation pathway. "activated coagulation time" is sometimes referred to as act. (12 Dec 1998) |