| DF | decapacitation factor; decontamination factor; deferoxamine; deficiency factor; defined flora [anima... |
|---|---|
| DGI | dentinogenesis imperfecta; disseminated gonococcal infection |
| DH | daily habits; day hospital; dehydrocholate; dehydrogenase; delayed hypersensitivity; dermatitis herp... |
| DIC | dicarbazine; differential interference contrast microscopy; diffuse intravascular coagulation; direc... |
| DISH | diffuse idiopathic skeletal hyperostosis; disseminated idiopathic skeletal hyperostosis |
| disseminated | Scattered, distributed over a considerable area. (16 Dec 1997) |
|---|---|
| disseminated choroiditis | Chronic inflammation of the choroid, with multiple isolated foci. (05 Mar 2000) |
| disseminated disease | Disease in which the cancerous cells have spread from the tissue of origin to other organs. (13 Nov 1997) |
| disseminated gonococcal infection | Infection from Neisseria gonorrhoea which is spread to distant parts of the body beyond the original portal of entry (usually the lower genital tract). Usually manifest by rash and arthritis. (05 Mar 2000) |
| disseminated intravascular coagulation | <haematology> Complication of septic shock in which endotoxin (from gram-negative bacteria) induces systemic clotting of the blood, probably indirectly through the effect of endotoxin on neutrophils. It may also develop in other situations where neutrophils become systemically hyperactivated. Acronym: DIC (11 Jan 1998) |
| disseminated lupus erythematosus | <immunology, nephrology, rheumatology> A disease of humans, probably autoimmune with antinuclear and other antibodies in plasma. Immune complex deposition in the glomerular capillaries is a particular problem. Acronym: SLE (19 Jan 1998) |
| disseminated necrotizing leukoencephalopathy | <radiology> DNL: demyelination due to radiation and chemotherapy, decreased density in deep white matter, with or without peripheral, patchy enhancement, calcification: basal ganglia, grey/white junction (12 Dec 1998) |
| disseminated sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
| disseminated tuberculosis | <microbiology> Usually a chronic tuberculosis infection where spread of the original primary infection has occurred via the patients lymphatic system (or bloodstream). Disseminated disease occurs primarily in the immunocompromised individual (for example AIDS, cancer patient). The elderly are at increased risk for dissemination. In disseminated disease, organs and tissues that can be affected include pericardium, peritoneum, larynx, bronchus, bone, joints, lymph nodes, stomach, meninges, eyes, kidneys and skin. Treatment is with INH, rifampin, ethambutol and other antibiotics. (11 Jan 1998) |
| encephalomyelitis, acute disseminated | An acute or subacute encephalomyelitis or myelitis characterised by perivascular lymphocyte and mononuclear cell infiltration and demyelination. It occurs most commonly following an acute viral infection, especially measles, but may occur without a recognizable antecedent, and formerly occurred as a complication of rabies and smallpox vaccination. (12 Dec 1998) |
| anergic leishmaniasis | Leishmaniasis caused by several New and Old World species and strains of Leishmania (L. Mexicana amazonensis, L. M. Pifanoi, possibly L. M. Garnhami and L. M. Venezuelensis; in Ethiopia, L. Aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the non-ulcerating, non-necrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not appear to occur unless an acquired cellular hypersensitivity can develop. Synonym: anergic leishmaniasis, diffuse leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa, pseudolepromatous leishmaniasis. (05 Mar 2000) |
| canine leishmaniasis | A mild infection of dogs, usually confined to the muzzle or ears, produced by human disease-causing species of Leishmania; dogs therefore are important reservoirs of human infection, such as with visceral leishmaniasis in the Mediterranean region. (05 Mar 2000) |
| visceral leishmaniasis | A chronic disease, occurring in India, Assam, China, the area formerly known as the Mediterranean littoral areas, the Middle East, India, Pakistan, China, South and Central America, Asia, Africa caused by Leishmania donovani and transmitted by the bite of an appropriate species of sandfly of the genus Phlebotomus or Lutzomyia; the organisms grow and multiply in macrophages, eventually causing them to burst and liberate amastigote parasites which then invade other macrophages; proliferation of macrophages in the bone marrow causes crowding out of erythroid and myeloid elements, resulting in leukopenia, and anaemia, splenomegaly, and hepatomegaly which are characteristic, along with enlargement of lymph nodes; fever, fatigue, malaise, and secondary infections also occur; different strains of leishmaniasis donovani occur; leishmaniasis infantum in Eurasia, leishmaniasis chagasi in Latin America. Synonym: Assam fever, black sickness, Burdwan fever, cachectic fever, Dumdum fever, kala azar, tropical splenomegaly. (05 Mar 2000) |
| mucocutaneous leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
| pseudolepromatous leishmaniasis | Leishmaniasis caused by several New and Old World species and strains of Leishmania (L. Mexicana amazonensis, L. M. Pifanoi, possibly L. M. Garnhami and L. M. Venezuelensis; in Ethiopia, L. Aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the non-ulcerating, non-necrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not appear to occur unless an acquired cellular hypersensitivity can develop. Synonym: anergic leishmaniasis, diffuse leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa, pseudolepromatous leishmaniasis. (05 Mar 2000) |