| digital reflex | <clinical sign> In latent tetany mild mechanical stimulation of the trigeminal nerve causes severe pain, flexion of the terminal phalanx of the thumb and of the second and third phalanges of one or more of the fingers when the volar surface of the terminal phalanx of the fingers is flicked. Synonym: digital reflex, Hoffmann's reflex, snapping reflex. (05 Mar 2000) |
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| digital subtraction angiography | Computer-assisted roentgenographic angiography permitting visualization of vascular structures without superimposed bone and soft tissue density; images made before and after contrast injection allow subtraction (separation and removal) of opacities not enhanced by the contrast medium. Other image-processing can be performed. Contrast material may be injected intravenously or in lower-than-usual amount intra-arterially. (05 Mar 2000) |
| digital veins | See: dorsal digital veins of foot, palmar digital veins, plantar digital veins. (05 Mar 2000) |
| digital whorl | <botany> A ring of leaves, bracts or floral parts borne at the same level on a main stem. (13 Nov 1997) |
| digitalin | C36H56O14;a standardised mixture of digitalis glycosides used as a cardiotonic. (05 Mar 2000) |
| digitalis | <pharmacology> General term for pharmacologically active compounds from the foxglove (Digitalis). The active substances are the cardiac glycosides, digoxin, digitoxin, strophanthin and ouabain. Causes increased force of contraction of the heart, disturbance of rhythm and reduced beat frequency. Also causes arteriolar constriction, venous dilation, nausea and visual disturbances. (03 Mar 1998) |
| digitalis glycosides | <chemical> Glycosides from plants of the genus digitalis. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all cardiac glycosides, but here is restricted to those related to digitalis. Pharmacological action: anti-arrhythmia agents, cardiotonic agent, enzyme inhibitors. (12 Dec 1998) |
| digitalis tincture | An hydroalcoholic solution containing the glycosides of the leaves of the foxglove (digitalis) plant Digitalis purpurea or D. Lanata. Although digitalis preparations are used extensively, they are currently used as the pure glycosides, digoxin and digitoxin. The tincture was formerly widely used but was standardised by bioassay using frogs, cats, or pigeons. (05 Mar 2000) |
| digitalis toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| digitalis unit | The activity of 0.1 g of the international standard powdered digitalis. (05 Mar 2000) |
| digitalisation | The administration of digitalis in a dosage schedule designed to produce and then maintain optimal therapeutic concentrations of its cardiotonic glycosides. (18 Nov 1997) |
| digitalism | The symptoms caused by digitalis poisoning or overdosage. (05 Mar 2000) |
| digitalization | Administration of digitalis by any one of a number of schedules until sufficient amounts are present in the body to produce the desired therapeutic effects. (05 Mar 2000) |
| digitate | Branching from the main stem or stalk like the fingers of a hand. (09 Oct 1997) |
| digitate dermatosis | See: parapsoriasis en plaque. Synonym: small plaque parapsoriasis. (05 Mar 2000) |