| adult T-cell lymphoma | <tumour> An acute or subacute disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcaemia. Synonym: adult T-cell leukaemia. (05 Mar 2000) |
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| anaplastic large cell lymphoma | <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2). Synonym: Ki-1+ lymphoma. (05 Mar 2000) |
| cutaneous T-cell lymphoma | <oncology, tumour> A type of non-Hodgkin's lymphoma that first appears on the skin. Synonym: mycosis fungoides. (13 Nov 1997) |
| human T-cell lymphoma/leukaemia virus | A group of viruses (subfamily Oncovirinae, family Retroviridae) that are lymphotropic with a selective affinity for the helper/inducer cell subset of T lymphocytes and that are associated with adult T-cell leukaemia and lymphoma. Synonym: human T-cell lymphotropic virus. (05 Mar 2000) |
| T-cell lymphoma | A cancer of the immune system that appears in the skin; also called mycosis fungoides. (12 Dec 1998) |
| follicular predominantly large cell lymphoma | <tumour> A B-cell lymphoma of intermediate malignancy. (05 Mar 2000) |
| large cell lymphoma | <oncology, tumour> Highly malignant group of tumours arising from transformed lymphocytes or myeloid precursors. Cell of origin often obscure. (18 Nov 1997) |
| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
| lymphoma, large-cell | A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter being more frequently seen. (12 Dec 1998) |
| lymphoma, large-cell, follicular | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. (12 Dec 1998) |
| lymphoma, large-cell, immunoblastic | Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (lymphoma, T-cell, peripheral) recorded in both the united states and japan. (12 Dec 1998) |
| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |
| lymphoma, mixed-cell | Malignant lymphoma characterised by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. (12 Dec 1998) |
| lymphoma, mixed-cell, follicular | A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. (12 Dec 1998) |
| lymphoma, T-cell | A group of heterogeneous lymphoid tumours representing malignant transformations of T-lymphocytes. (12 Dec 1998) |