| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| 영문 | infectious disease | 한글 | 감염병 |
|---|---|---|---|
| 설명 | 바이러스로부터 기생충 크기까지의 생물을 원인으로 하는 병. 원인은 접촉전염성이며, 병원에서 감염되는 경우도 있다. 감염을 원인균에 따라 분류하면 바이러스, 세균, 클라미디아, 리켓차, 미코박테리움, 곰팡이, 원충, 윤충, 외부기생충 감염으로 나눌 수 있다. |
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| 영문 | hypertensive heart disease | 한글 | 고혈압심장병 |
|---|---|---|---|
| 설명 | 고혈압에 의해서 생기는 심장병. 고혈압심장병이라는 진단을 붙이기 위해서는 최소한 다음과 같은 조건이 부합되어야 하는데, 첫째 심장혈관계에 심장병을 유발할 수 있을 만한 다른 병변이 없이 좌심실 비대가 있어야 하며, 둘째 고혈압을 앓았다는 병력이 있어야 한다. 주로 고혈압에 의한 심장병은 초기에는 좌심실이 비후라는 것으로 특징되어진다. 즉 혈압이 높으므로 혈액을 순환시키기 위해서는 그만큼 심장의 혈액을 보내는 힘이 좋아야 한다. 그 힘을 얻기위해서는 심근의 비후가 필요로 하여 좌심실 근육의 비후가 생긴다. 그리고 고혈압이 지속이 될 경우에는 결국 심장이 제 구실을 하지 못하고 펌프로서의 기능을 잃어버리게 되어 심장기능상실에 빠지게 된다. |
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| 영문 | pelvic inflammatory disease | 한글 | 골반염질환 |
|---|---|---|---|
| 설명 | 골반주위의 장기에 발생하는 염증을 말함. 주로 여성에서 발생하며 원인은 임균(gonococcus)과 비임균에 의한 감염(non-gonorrheal infection)에 의한다. 증상은 초기에는 질분비물, 하복부동통, 여성의 생식기부위에 발생하는 압통, 월경통, 월경량의 증가 등이다. 일찍 치료해야 하며, 계속적으로 병이 지속시 여성의 불임의 원인이 된다. 후진국에서는 가장 많은 여성불임의 원인이기도 함. 치료는 항생제의 투여이다. |
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| HD | Haab-Dimmer [syndrome]; Hajna-Damon [broth]; Hansen disease; hearing distance; heart disease; helix ... |
|---|---|
| MD | Doctor of Medicine [Lat. Medicinae Doctor]; magnesium deficiency; main duct; maintenance dose; major... |
| MBD | Marchiafava-Bignami disease; Mental Deterioration Battery; methylene blue dye; minimal brain damage;... |
| AD | accident dispensary; acetate dialysis; active disease; acute dermatomyositis; addict, addiction; ade... |
| PD | Doctor of Pharmacy; Dublin Pharmacopoeia; interpupillary distance; Paget disease; pancreatic duct; p... |
| base of brain | The inferior surface of the brain visible when seen from below. Synonym: facies inferior cerebri, basis cerebri, inferior cerebral surface. (05 Mar 2000) |
|---|---|
| big brain | <molecular biology> Neurogenic gene of Drosophila, believed to encode a product involved in cell cell communication, perhaps via gap junctions. Member of the major intrinsic protein family. (18 Nov 1997) |
| blood-brain barrier | <pharmacology, physiology> A protective barrier formed by the blood vessels and glia of the brain. It prevents some substances in the blood from entering brain tissue. The blood vessels of the brain (and the retina) are much more impermeable to large molecules (like antibodies) than blood vessels elsewhere in the body. This has important implications for the ability of the organism to mount an immune response in these tissues, although the basis for the difference in endothelial permeability is not well understood. (16 Dec 1997) |
| brain | One of the two components of the central nervous system, the brain is the centre of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). (22 May 1997) |
| brain abscess | A localised cavity filled with pus secondary to a bacterial infection. (27 Sep 1997) |
| brain abscess in kids | <radiology> Cyanotic congenital heart disease, e.g., tetralogy of Fallot, most important predisposing factor, blood not filtered by pulmonary capillaries (12 Dec 1998) |
| brain aneurysm | A dilated and weakened portion of a cerebral blood vessel that is prone to rupture. A cerebral aneurysm may occur as a birth defect or develop as the result of long-standing poorly controlled hypertension. Symptoms of a ruptured cerebral aneurysm include a sudden, severe thunderclap headache that may be associated with nausea, vomiting and a decreased level of consciousness. (27 Sep 1997) |
| brain-assocated tyrosine kinase | <enzyme> 86% identical to matk protein. Registry number: EC 2.7.1.- Synonym: batk protein (26 Jun 1999) |
| brain cicatrix | A scarring of the brain resulting from injury (reactive gliosis), characterised by proliferation of mesodermal (vascular) and ectodermal (glial) elements. See: isomorphous gliosis. (05 Mar 2000) |
| brain concussion | Transient or prolonged unconsciousness with or without impairment of higher mental functions and/or brainstem functions, due to a violent blow to the head. (12 Dec 1998) |
| brain congestion | Increased volume of the intravascular compartment of the brain; often associated with brain swelling. Synonym: encephalaemia. (05 Mar 2000) |
| brain contusion | A head injury of sufficient force to bruise the brain. The bruising of the brain will often involve the surface of the brain and cause an extravasation of blood without rupture of the pia-arachnoid. Often associated with a concussion. (27 Sep 1997) |
| brain death | Total cessation of brain function for 24 hours as manifested by absence of spontaneous movement, absence of spontaneous respiration, and absence of all brainstem reflexes. (12 Dec 1998) |
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |