| 영문 | hyaline membrane disease | 한글 | 유리질막병 |
|---|---|---|---|
| 설명 | 허파 성숙도의 미숙으로 허파꽈리를 팽창시키는 물질(표면활성제)이 부족하여 호흡곤란이 초래되는 병으로서 미숙아에 호발하는데, 출생시 임신기간보다도 허파 성숙 정도가 더 관여된다. 단일 병으로서는 사망률이 가장 높으며(약 30%), 신생아의 대표적인 병이다. 임상적으로는 미숙아, 생후 6~8시간내 호흡곤란증세 출현과 생후 24~48시간의 증상 악화, 생후 2~3일간 인공적으로 산소를 공급하지 않으면 호흡을 계속시킬 수가 없으며 점점더 산소의 공급 의존도가 높아지며, 동맥혈액속의 산소농도가 내려가고 이산화탄소의 농도가 높으며, 흉부 방사선 소견을 참작하여 진단한다. 환아는 숙련된 간호 인력과 첨단 의료 장비가 설치된 신생아 집중 치료실에서 치료하여야 한다. 예후는 증세의 경중에 따라 다르고 사망률은 30~50% 된다. 어떤 아기에 있어서는 치료 후에 눈이나 기관지허파 계통에 장애를 일으키는 산소중독증이 보고되고 있다. |
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| 영문 | plasma membrane | 한글 | 형질막 |
|---|---|---|---|
| 설명 | 원형질 표면을 덮는 엷은막. 두께는 5~25μm이다. 광학현미경으로는 관찰할 수 없지만 전자현미경으로 관찰이 가능하다. 원형질막의 분자구조는 레시틴이나 콜레스테롤 등의 표면 활성물질 분자가 2분자층으로 그 표면에 배열되며, 이것을 각 1분자층의 단백질 분자가 양쪽에서 샌드위치한 단위막 구조이다. 전자현미경적으로 이 단위는 암-명-암의 3층(각 약 20nm)으로 구별된다. 원형질의 투과성에 중요한 구실을 하며, 생리상태가 변하면 그 투과성도 신속히 변한다. 또, 손상이 되면 쉽게 새로 형성된다. |
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| PROM | 1) Premature Rupture of Amniotic Membrane; < Labor Onset 2) Preterm Ruptu... |
|---|---|
| BLM | bilayer lipid membrane; bimolecular liquid membrane; bleomycin; buccolinguomasticatory |
| BM | Bachelor of Medicine; barium meal; basal medium; basal metabolism; basement membrane; basilar membra... |
| CM | California mastitis [test]; calmodulin; capreomycin; carboxymethyl; cardiac murmur; cardiac muscle; ... |
| EMP | electric membrane property; electromagnetic pulse; Embden-Meyerhof pathway; external membrane potent... |
| congenital ectodermal defect | Incomplete development of the epidermis and skin appendages; the skin is smooth and hairless, the facies abnormal, and the teeth and nails may be affected; sweating may be deficient. Synonym: congenital ectodermal dysplasia. (05 Mar 2000) |
|---|---|
| coupling defect | See: familial goiter. (05 Mar 2000) |
| postinfarction ventricular septal defect | A defect developed in the ventricular septum resulting from rupture of an acute myocardial infarction. (05 Mar 2000) |
| salt-losing defect | Renal tubular abnormality causing loss of sodium in the urine. (05 Mar 2000) |
| septal defect, atrial | A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an asd. Asds are a major class of heart deformity that is present at birth (congenital cardiac malformation). (12 Dec 1998) |
| septal defect, ventricular | A hole in the interventricular septum, the wall between the ventricles, the lower chambers of the heart. Commonly called a vsd. Vsds are a common class of heart deformity that is present at birth (congenital cardiac malformation). (12 Dec 1998) |
| neural tube defect | <neurology, paediatrics> Abnormal development during embryonic life of the neural tube producing congenital malformations of the nervous system due to closure failure of the neural tube. The structure gives rise to the central nervous system (the brain and spinal cord), and failure to close results in anencephaly (absence of the cranial vault and absence of most or all of the cerebral hemispheres of the brain) and spina bifida or meningomyelocele (open spina with exposure and protusion of the spinal cord). The risk of neuroal tube defects can be decreased by the mother taking folic acid during pregnancy. (04 Jul 1999) |
| defect | 1. Want or absence of something necessary for completeness or perfection; deficiency; opposed to superfluity. "Errors have been corrected, and defects supplied." (Davies) 2. Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment. "Trust not yourself; but, your defects to know, Make use of every friend any every foe." (Pope) "Among boys little tenderness is shown to personal defects." (Macaulay) Synonym: Deficiency, imperfection, blemish. See Fault. Origin: L. Defectus, fr. Deficere, defectum, to desert, fail, be wanting; de- + facere = to make, do. See Fact, Feat, and cf. Deficit. Source: Websters Dictionary (01 Mar 1998) |
| defect, atrial septal | A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an ASD. ASDs are a major class of congenital cardiac malformation. (12 Dec 1998) |
| defect, enzyme | An abnormality in the protein (enzyme) important in catalyzing a normal biochemical reaction in the body. Disorders result from a deficiency (or functional abnormality) of an enzyme. Archibald Garrod in 1902 was the first to attribute a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as phenylketonuria (PKU) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| defect, ventricular septal | Hole in the interventricular septum, the wall between the ventricles (lower chambers of the heart). Commonly called a VSD. VSDs are a common class of heart deformity present at birth (congenital cardiac malformation). (17 Dec 1998) |
| iodide transport defect | See: familial goiter. (05 Mar 2000) |
| iodotyrosine deiodinase defect | See: familial goiter. (05 Mar 2000) |
| oesophageal filling defect | <radiology> Tumour, carcinoma (oesophagus, stomach extending proximally), leiomyoma / leiomyosarcoma, polyp: fibrovascular, inflammatory, adenomatous, papilloma, carcinosarcoma, lymphoma, metastasis, oesophageal varix, extrinsic lesion (vascular impression, adenopathy, cyst), foreign body (12 Dec 1998) |
| osteoporotic marrow defect | Focal osteoporotic bone marrow defect of the jaw; a focal radiolucent defect composed of normal marrow. (05 Mar 2000) |