cytochrome : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 2

Cytochrome P-450 CYP1A1 - 새창 A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Synonyms : 7-Ethoxyresorufin O-Deethylase, CYP 1A1, CYP1A1 Protein, Cytochrome P450 IA1, Ethoxyresorufin Dealkylase, Ethylresorufin O-Deethylase, Cytochrome P 450 CYP1A1
Cytochrome P-450 CYP1A2 - 새창 A cytochrome P-450 monooxygenase that can be induced by polycyclic aromatic xenobiotics in the liver of human and several animal species. This enzyme is of significant clinical interest due to the large number of drug interactions associated with its induction and its metabolism of THEOPHYLLINE. Caffeine is considered to be a model substrate for this enzyme. CYP1A2 activity can also be increased by environmental factors such as cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole.
Synonyms : CYP 1A2, Caffeine Demethylase, Cytochrome P-450 LM(4), Cytochrome P-450 LM4, Cytochrome P-450d, Cytochrome P450 1A2, CYP1A2, Cytochrome P-450, Cytochrome P 450 CYP1A2, Cytochrome P 450d, Demethylase, Caffeine, O-Dealkylase, Phenacetin, Phenacetin O Dealkylase
Cytochrome P-450 CYP27A1 - 새창 An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha, 12-alpha-triol. Cytochrome P-450 CYP27A1 is a mitochondrial enzyme; however microsomal-derived homologs of the enzyme have been identified and are included under this heading.
Synonyms : 5-beta-Cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-Hydroxylase, C27-Steroid 26-Hydroxylase, Cholestanetriol 26-Monooxygenase, Cytochrome P-450 CYP2R1, Cytochrome P-450 Steroid 27-Hydroxylase, Cytochrome P-450 Sterol 26-Hydroxylase, Cytochrome P450 2R1
Cytochrome P-450 CYP2B1 - 새창 A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Synonyms : 7-Benzyloxyresorufin O-Dealkylase, 7-Pentylresorufin O-Depentylase, CYP 2B1, Cytochrome P450 2B1, 7 Benzyloxyresorufin O Dealkylase, 7 Pentylresorufin O Depentylase, Benzyloxyresorufin O Dealkylase, Cytochrome P 450 CYP2B1, O-Dealkylase, Pentoxyresorufin
Cytochrome P-450 CYP2D6 - 새창 A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
Synonyms : CYP 2D6, Cytochrome P450 2D6, Debrisoquine 4-Monooxygenase, Imipramine 2-Hydroxylase, Sparteine Monooxygenase, 2-Hydroxylase, Imipramine, 4-Hydroxylase, Debrisoquine, 4-Monooxygenase, Debrisoquine, CYP2D6, Cytochrome P-450, Cytochrome P 450 CYP2D6