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argininosuccinate lyase <enzyme> An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease argininosuccinic acidemia in man.
Chemical name: N-(L-Argininosuccinate) arginine-lyase
Registry number: EC 4.3.2.1
(12 Dec 1998)
aspartate ammonia-lyase <enzyme> An enzyme that catalyses the conversion of aspartic acid to ammonia and fumaric acid in plants and some microorganisms.
Chemical name: L-Aspartate ammonia-lyase
Registry number: EC 4.3.1.1
(12 Dec 1998)
ATP citrate lyase ATP citrate (pro-3S)-lyase
ATP citrate (pro-3S)-lyase <enzyme> An enzyme that, in the presence of ATP and CoA, catalyses the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and orthophosphate. This reaction represents an important step in fatty acid biosynthesis.
Chemical name: ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating)
Registry number: EC 4.1.3.8
Synonym: citrate cleavage enzyme.
(12 Dec 1998)
benzaldehyde lyase <enzyme> Requires thiamine ppi; from pseudomonas fluorescens; cleaves the acycloin linkage of benzoin, producing 2 molecules of benzaldehyde; also acts on anisoin, forming anisaldehyde
Registry number: EC 4.1.2.-
Synonym: benzoin benzaldehyde lyase
(26 Jun 1999)
carbonate hydro-lyase carbonic anhydrase
carbon-phosphorus lyase <enzyme> Found in bacteria which utilise alkyl and phenylphosphonic acids
Registry number: EC 4.99.-
Synonym: c-p lyase, carbon-phosphorus cleavage enzyme
(26 Jun 1999)
malate ATP lyase <chemical> Composed of malyl-CoA synthetase (EC 6.2.1.9) and malyl-CoA lyase (EC 4.3.24)
Synonym: malate lyase
(26 Jun 1999)
malate carboxy-lyase <enzyme> Decarboxylates l-malic acid to l-lactic acid and co2 with traces of pyruvic acid
Registry number: EC 4.1.1.-
(26 Jun 1999)
mandelonitrile lyase <enzyme> Catalyses the reversible condensation of hcn with aldehydes to form d-alpha-hydroxynitriles; contains fad
Registry number: EC 4.1.2.10
Synonym: mandelonitrile benzaldehyde-lyase, oxynitrilase
(26 Jun 1999)
gellan lyase <enzyme> Cleaves beta-d-glucosyl-1-4-beta-d-glucuronosyl sequence in gellan
Registry number: EC 4.2.2.-
Synonym: gellanase
(26 Jun 1999)
glucuronan lyase <enzyme> Catalyses beta-elimination cleavage of acetylated and deacetylated (1->4)-beta-d-glucuronan
Registry number: EC 4.2.2.-
(26 Jun 1999)
pectin lyase <enzyme> Catalyses elimination of 6-methyl-delta-4,5-galacturonate residues from pectin; brings about depolymerization of pectin; does not act on deesterified pectin
Registry number: EC 4.2.2.10
Synonym: poly(methoxygalacturonide)lyase, protopectinase-r, ppase-r, pnla protein, pnla gene product, psx1 gene product, polymethoxygalacturonase
(26 Jun 1999)
peptidylamidoglycolate lyase <enzyme> Second step in the production of alpha-amidated peptides from their glycine-extended precursors; first step is EC 1.14.17.3 (amide synthetase)
Registry number: EC 4.3.2.5
Synonym: pahgaa lyase, peptidyl-alpha-hydroxyglycine alpha amidating lyase, peptidylhydroxyglycine n-c lyase
(26 Jun 1999)
chondroitin abc lyase <enzyme> An enzyme that catalyses the eliminative degradation of polysaccharides containing 1,4-beta-d-hexosaminyl and 1,3-beta-d-glucuronosyl or 1,3-alpha-l-iduronosyl linkages to disaccharides containing 4-deoxy-beta-d-gluc-4-enuronosyl groups. (enzyme nomenclature, 1992)
Chemical name: chondroitin ABC lyase
Registry number: EC 4.2.2.4
(12 Dec 1998)
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