| guanylate cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
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| guanyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| purine imidazole-ring cyclase | <enzyme> Recyclises ring-opened purine formamidopyrimidines in irradiated DNA, restoring the c-8 to n-9 band, does not require ATP Registry number: EC 6.3.3.- Synonym: purir cyclase (26 Jun 1999) |
| humulene cyclase | <enzyme> Catalyses the cyclization of farnesyl pyrophosphate; probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation which is stabilised by deprotonation at c-9 to form all-trans humulene; mw 57 kD Registry number: EC 5.- (26 Jun 1999) |
| squalene cyclase | <enzyme> Nonoxidative conversion of squalene to tetrahymenol; does not go via 2,3-oxidosqualene Registry number: EC 4.- Synonym: squalene-tetrahydromanol cyclase (26 Jun 1999) |
| squalene epoxidase-cyclase | <chemical> Consists of squalene epoxidase (EC 1.14.99.7) plus 2,3-oxidosqualene lanosterol-cyclase (EC 5.4.99.7) Chemical name: squalene-2,3-oxide lanosterol cyclase (26 Jun 1999) |
| squalene-hopene cyclase | <enzyme> From bacillus acidocaldarius; cyclises squalene into hopanoid triterpenes Registry number: EC 5.4.99.- Synonym: shc gene product (26 Jun 1999) |
| diguanylate cyclase | <enzyme> Converts 2GTP to bis-(3'-5')cyclic guanylic acid, via linear diguanosine tetraphosphate pppg 3'p5'g, releasing 1 pyrophosphate at each step Registry number: EC 4.6.1.- (26 Jun 1999) |
| tetracenomycin F2 cyclase | <enzyme> Catalyses the cyclization of the anthrone tcmf2 to the naphthacenone tcmf1 in the biosynthesis of antibiotic tcm c in streptomyces glaucescens by an intramolecular aldol condensation-dehydration Registry number: EC 4.1.2.- Synonym: tcmi protein (26 Jun 1999) |
| thienamycin cyclase | <enzyme> Isolated from streptomyces lividans Registry number: EC 5.- (26 Jun 1999) |
| tocopherol cyclase | <enzyme> Catalyses cyclization of phytyl-hydroquinone to gamma-tocopherol; isolated from the blue-green alga anabaena variabilis Registry number: EC 5.4.99.- (26 Jun 1999) |
| endo-fenchol cyclase | <enzyme> Converts geranyl pyrophosphate to (-)-endo-fenchol via (-)-(3r)-linoyl pyrophosphate Registry number: EC 5.5.- (26 Jun 1999) |
| epinephrine cyclase | <enzyme> Epinephrine is converted to adrenochrome Registry number: EC 1.10.3.- Synonym: catecholamine cyclase (26 Jun 1999) |
| UDPglucuronic acid cyclase | <enzyme> Forms udpapiose plus carbon dioxide Registry number: EC 4.1.1.- Synonym: udpglucuronic carboxy-lyase (cleaving, cyclizing) (26 Jun 1999) |