| nephrosis | A type of nephritis that is characterised by low serum albumin, large amount of protein in the urine and swelling (oedema). Swelling, weight gain, high blood pressure and anorexia are key features. Nephrotic syndrome can be seen with a number of illness that cause damage to the kidney glomerulus. Examples include diabetes, hereditary disorders, lupus, multiple myeloma, amyloidosis, glomerulonephritis, minimal change disease and membranous glomerulonephritis. (27 Sep 1997) |
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| nephrosis, lipoid | Glomerular disease causing heavy proteinuria characterised by absence of obvious histologic glomerular changes on light microscopy. It is also called minimal change glomerular disease and minimal lesion glomerulonephritis. (12 Dec 1998) |
| osmotic nephrosis | Swelling of renal tubular epithelium associated with glomerular filtration of sugars and dextrose; the swelling is due to formation of cytoplasmic vesicles by pinocytosis, and is reversible, probably with no dysfunction, when produced by glucose or mannitol. (05 Mar 2000) |
| toxic nephrosis | Acute oliguric renal failure due to chemical poisons, septicaemia, or bacterial toxaemia; frequently associated with extensive necrosis of proximal convoluted tubules. (05 Mar 2000) |
| familial nephrosis | The nephrotic syndrome appearing in sibs in infancy, without nerve deafness. (05 Mar 2000) |
| lipoid nephrosis | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome in children affecting 2 to 3 children per 100,000 population under age 16 in the us. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. (27 Sep 1997) |
| lower nephron nephrosis | An obsolete term for acute tubular necrosis. (05 Mar 2000) |