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proton pump Integral membrane proteins that transport protons across a membrane against a concentration gradient. This transport is driven by hydrolysis of ATP by hydrogen-transporting ATP synthase.
(12 Dec 1998)
proton pump inhibitor <pharmacology> A group of anti-ulcer medications which work by binding to H+/K+ ATPase, an enzyme which is found on the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with potasium) into the gastric lumen.
Examples of proton pump inhibitors include omeprazole and lansoprazole.
(27 Sep 1997)
hogger-pump <chemical> The for pump in the pit.
Source: Websters Dictionary
(01 Mar 1998)
pump An hydraulic machine, variously constructed, for raising or transferring fluids, consisting essentially of a moving piece or piston working in a hollow cylinder or other cavity, with valves properly placed for admitting or retaining the fluid as it is drawn or driven through them by the action of the piston.
For various kinds of pumps, see Air pump, Chain pump, and Force pump; also, under Lifting, Plunger, Rotary, etc. Circulating pump See Well.
Origin: Akin to D. Pomp, G. Pumpe, F. Pompe; of unknown origin.
Source: Websters Dictionary
(01 Mar 1998)
pump failure A term used to emphasize mechanical default of the heart as a pump; in acute myocardial infarction, pump failure signifies congestive heart failure, pulmonary oedema, or cardiogenic shock.
Compare: electrical failure.
Synonym: power failure.
(05 Mar 2000)
pump lung In shock, the development of oedema, impaired perfusion, and reduction in alveolar space so that the alveoli collapse.
Synonym: pump lung, wet lung, white lung.
(05 Mar 2000)
pump-oxygenator A machine that does the work both of the heart (pump blood) and the lungs (oxygenate the blood). Used, for example, in open heart surgery. Blood returning to the heart is diverted through the machine before returning it to the arterial circulation. Also called a heart-lung machine.
(12 Dec 1998)
hydrogen pump Molecular mechanism for acid secretion from gastric parietal cells based on the activity of a H+-K+-ATPase.
(05 Mar 2000)
sodium-potassium pump A membrane-bound transporter that maintains the high potassium and low sodium intracellular concentrations relative to the extracellular medium. This exchange is accomplished at the expense of cellular energy in the form of ATP.
(05 Mar 2000)
sodium pump <enzyme> A major transport protein of the plasma membrane. A multi unit enzyme, it moves 3 sodium ions out of the cell and 2 potassium ions in, for each ATP hydrolysed. The sodium gradient established is used for several purposes (see facilitated diffusion, action potential), while the potassium gradient is dissipated through the potassium leak channel. Must not be confused with a sodium channel.
(18 Nov 1997)
sprengel pump <physics> A form of air pump in which exhaustion is produced by a stream of mercury running down a narrow tube, in the manner of an aspirator; named from the inventor.
Source: Websters Dictionary
(01 Mar 1998)
Staphylococcal neutral phosphatase <enzyme> A surface-bound bacterial protein; highly cationic; shows maximum phosphatase activity at neutral pH; binds to immunoglobulin
Registry number: EC 3.1.3.-
Synonym: staphylococcal nptase, nptase
(26 Jun 1999)
Staphylococcus aureus neutral proteinase <enzyme> Included in the group of microbial metalloproteinases EC 3.4.24.4; ptrb protein is isolated from E coli; sakstar is recombinant staphylokinase
Pharmacological action: fibrinolytic agents
Registry number: EC 3.4.24.-
Synonym: protease II, staphylokinase, staph aureus protease, staphylococcal protease, E coli protease, ptrb protein, sakstar,
(26 Jun 1999)
stomach pump An apparatus for removing the contents of the stomach by means of suction.
(05 Mar 2000)
neutral 1. Not engaged on either side; not taking part with or assisting either of two or more contending parties; neuter; indifferent. "The heart can not possibly remain neutral, but constantly takes part one way or the other." (Shaftesbury)
2. Neither good nor bad; of medium quality; middling; not decided or pronounced. "Some things good, and some things ill, do seem, And neutral some, in her fantastic eye." (Sir J. Davies)
3. <biology> Neuter. See Neuter.
4. <chemistry> Having neither acid nor basic properties; unable to turn red litmus blue or blue litmus red; said of certain salts or other compounds. Contrasted with acid, and alkaline.
<chemistry> Neutral axis, Neutral surface, a salt formed by the complete replacement of the hydrogen in an acid or base; in the former case by a positive or basic, in the latter by a negative or acid, element or radical. Neutral tint, a bluish gray pigment, used in water colours, made by mixing indigo or other blue some warm colour. The shades vary greatly. Neutral vowel, the vowel element having an obscure and indefinite quality, such as is commonly taken by the vowel in many unaccented syllables. It is regarded by some as identical with the u in up, and is called also the natural vowel, as unformed by art and effort.
Origin: L. Neutralis, fr. Neuter. See Neuter.
Source: Websters Dictionary
(01 Mar 1998)
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