| HIV core protein p24 | A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by elisa and western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines. (12 Dec 1998) |
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| disease, central core, of muscle | <anatomy> One of the conditions that produces 'floppy baby' syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). CCD is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). (12 Dec 1998) |
| absolute temperature | Temperature reckoned in Kelvins from absolute zero. (05 Mar 2000) |
| basal body temperature | <biology> The temperature taken at its lowest point in the day, usually in the morning before getting out of bed. (09 Oct 1997) |
| body temperature changes | Any deviation from normal body temperature of the human body, about 98.6 degrees f. Or 37 degrees c. When taken orally. (12 Dec 1998) |
| maximum temperature | In bacteriology, denoting a temperature above which growth will not take place. (05 Mar 2000) |
| mean temperature | The average atmospheric temperature in any locality for a designated period of time, as a month or a year. (05 Mar 2000) |
| restrictive temperature | <molecular biology> Of a temperature sensitive mutation, a temperature at which the mutated gene product behaves normally and so the cell or organism survives as if wild type. C.f. The restrictive temperature, at which the gene product takes on a mutant phenotype. (18 Nov 1997) |
| melting temperature | The midpoint in the change in optical properties (absorbance, rotation) of a structured polymer (e.g., DNA) with increasing temperature. Synonym: melting temperature. (05 Mar 2000) |
| melting temperature of DNA | That temperature at which, under a given set of conditions, double-stranded DNA is changed (50%) to single-stranded DNA; under standard conditions, the base composition of the DNA can be estimated from the denaturation temperature, since the greater the denaturation temperature, the greater the guanine-plus-cytosine content (i.e., GC content) of the DNA. Synonym: melting temperature of DNA. (05 Mar 2000) |
| permissive temperature | <molecular biology> Of a temperature sensitive mutation, a temperature at which the mutated gene product behaves normally and so the cell or organism survives as if wild type. C.f. The restrictive temperature, at which the gene product takes on a mutant phenotype. (18 Nov 1997) |
| room temperature | The ordinary temperature (65 |
| minimum temperature | In bacteriology, denoting a temperature below which growth will not take place. (05 Mar 2000) |
| critical temperature | The temperature of a gas above which it is no longer possible by use of any pressure, however great, to convert it into a liquid. (05 Mar 2000) |
| sensible temperature | The atmospheric temperature as felt by the individual, supposed to be that recorded by the wet-bulb thermometer. (05 Mar 2000) |