| continuous positive pressure breathing | Artificial ventilation in which all inspirations are provided by positive pressure applied to the airway. Synonym: continuous positive pressure breathing, continuous positive pressure ventilation, intermittent positive pressure breathing, intermittent positive pressure ventilation. (05 Mar 2000) |
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| continuous positive pressure ventilation | Synonym: controlled mechanical ventilation. (05 Mar 2000) |
| continuous processing | A method of bioprocessing in which new materials are added and products removed continuously at a rate that maintains the volume at a specific level. (14 Nov 1997) |
| continuous random variable | Continuous variable that may randomly assume any value in its domain but any particular value has no probability of occurring, only a probability density. (05 Mar 2000) |
| continuous spectrum | A spectrum in which there are no absorption bands or lines. (05 Mar 2000) |
| continuous spinal anaesthesia | Insertion of a catheter into the spinal subarachnoid space and leaving it in situ to permit serial intermittent injection of local anaesthetic solution for prolonged spinal anaesthesia. Synonym: fractional spinal anaesthesia. (05 Mar 2000) |
| continuous suture | An uninterrupted series of stitches using one suture; the stitching is fastened at each end by a knot. Synonym: spiral suture, uninterrupted suture. (05 Mar 2000) |
| continuous time model | <epidemiology> A model in which the system changes continuously over time. Derivatives (e.g. DY/dt ) are the mathematical formalism for describing such continuous change. The differential equation which embodies a model provides the values of these derivatives at any particular time point; calculus or a computer can then be used to move the state of the model forwards in time. Continuous models have the advantage over discrete time models in that they are more amenable to algebraic manipulation, although they are slightly harder to implement on a computer. The same as a differential equation model. (05 Dec 1998) |
| continuous tremor | A tremor that is constant, whether the subject is at rest or moving. Synonym: continuous tremor. (05 Mar 2000) |
| continuous variable | A variable that may take on any value in an interval or intervals (its domain). (05 Mar 2000) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acceleration phase | <cell biology, cell culture> A period of increasing growth before the log phase in a culture of microbes. After the culture is started on a medium, at first there is no growth (the lag phase) and then the microbes start to gradually grow (acceleration phase) until they reach a constant maximum rate of growth (log phase). (15 Jan 1998) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acute-phase reaction | <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms. It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors. (12 Jul 2000) |
| anal phase | In psychoanalytic personality theory, the stage of psychosexual development, occurring when a child is between 1 and 3 years, during which activities, interests, and concerns are centreed around the anal zone. (05 Mar 2000) |