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nonsuppressible insulin-like activity A blood protein (nsila) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of cohn fraction III, 10% of the activity is found in the supernatant (nsila-s) and the remaining activity in the precipitate (nsila-p). The latter is a large molecular compound, much less stable than the soluble fraction. Nsila-s is a more potent growth factor than insulin and exhibits sulfation activity.
(12 Dec 1998)
drug activity A measure of the physiological response a drug produces. A less active drug produces less response (and visa versa).
(12 Dec 1998)
insulin-like activity A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin.
(05 Mar 2000)
intrinsic sympathomimetic activity The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system.
(05 Mar 2000)
optical activity The ability of a material to rotate the plane of polarized light.
(09 Oct 1997)
triggered activity One or a series of spontaneously generated heart beats originating from an action potential that produces an after-depolarisation which reaches activation threshold.
(05 Mar 2000)
unit of thyrotrophic activity The activity of an amount of an extract of the anterior lobe of the hypophysis which, given daily for 5 days, will cause the thyroid of a guinea pig (weighing 200 g) to reach a weight of 600 mg.
(05 Mar 2000)
zone of polarizing activity <cell biology> The small group of mesenchyme cells in avian limb buds that is located at the posterior margin of the developing bud and that produces a substance, possibly retinoic acid, that provides positional information to the developing limb bud.
(18 Nov 1997)
peritoneal dialysis, continuous ambulatory Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution.
(12 Dec 1998)
mixed discrete-continuous random variable <statistics> A random variable that may assume some values with probabilities and others with probability densities.
For example, in a 35-year-old man with familial polyposis of the colon, the distribution of time until malignant disease occurs consists of a probability that he already has cancer (which would be assigned the waiting time 0), a probability density of developing it in the future and a probability that he will die of some other cause before he develops cancer.
(05 Mar 2000)
motion therapy, continuous passive Movement of a body part initiated and maintained by a mechanical or electrical device to restore normal range of motion to joints, muscles, or tendons after surgery, prosthesis implantation, contracture flexion, or long immobilization.
(12 Dec 1998)
continuous Not interrupted, having no interruption.
Origin: L. Continuus
(18 Nov 1997)
continuous ambulatory peritoneal dialysis Method of peritoneal dialysis performed in ambulatory patients with influx and efflux of dialysate during normal activities.
(05 Mar 2000)
continuous bar retainer A metal bar, usually resting on lingual surfaces of teeth, to aid in their stabilization and to act as indirect retainer's.
Synonym: continuous clasp.
(05 Mar 2000)
continuous beam In dentistry, a beam that continues over three or more supports, those supports not at the beam ends being equally free supports.
(05 Mar 2000)
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