| GCT | general care and treatment; germ-cell tumor; giant cell thyroiditis; giant cell tumor |
|---|---|
| CAV | congenital absence of vagina; congenital adrenal virilism; constant angular velocity; croup-associat... |
| CC | calcaneal-cuboid; calcium cyclamate; cardiac catheterization; cardiac contusion; cardiac cycle; card... |
| CHA | Canadian Hospital Association; Catholic Health Association; Chinese hamster; chronic hemolytic anemi... |
| CHD | Chediak-Higashi disease; childhood disease; chronic hemodialysis; congenital or congestive heart dis... |
| pigmented liver | A liver that contains pigment, such as occurs in Dubin-Johnson syndrome, haemochromatosis, long-standing malaria. (05 Mar 2000) |
|---|---|
| pigmented part of retina | pigmented part of retina |
| pigmented purpuric lichenoid dermatosis | An eruption comprised of lichenoid papules variously pigmented from the haemosiderin of the associated purpura; found on the legs, usually in men over 40 years of age. Synonym: Gougerot and Blum disease. (05 Mar 2000) |
| pigmented retinal epithelium | Layer of unusual phagocytic epithelial cells lying below the photoreceptors of the vertebrate eye. The dorsal surface of the PRE cell is closely apposed to the ends of the rods and as discs are shed from the rod outer segment they are internalised and digested by the PRE. Do not have desmosomes or cytokeratins in some species. (18 Nov 1997) |
| pigmented villonodular synovitis | <radiology> Monoarthritis, young adults, erosions on BOTH sides of joint (!), probably inflammatory, haemosiderin deposited in synovium, articular cartilage preserved (despite extensive marginal erosions; similar to gout), NO calcification Differential diagnosis: TB (associated atrophy of muscle and bone), rheumatoid arthritis (symmetrical), synovial sarcoma (with or without calcified; outside joint), synovial osteochondromatosis (12 Dec 1998) |
| synovitis, pigmented villonodular | Outgrowths of synovial membrane composed of villi and fibrous nodules characterised histologically by haemosiderin- and lipid-containing macrophages and multinucleated giant cells. It usually occurs in the knee. (12 Dec 1998) |
| benign giant lymph node hyperplasia | Solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes, occurring usually in the mediastinum or hilar region of young adults; similar changes have been reported outside the mediastinum and, if associated with interfollicular sheets of plasma cells, may progress to lymphoma or plasmacytoma. Synonym: angiofollicular mediastinal lymph node hyperplasia, Castleman's disease. (05 Mar 2000) |
| carcinoma, giant cell | An epithelial neoplasm characterised by unusually large anaplastic cells. It is highly malignant with fulminant clinical course, bizarre histologic appearance and poor prognosis. It is most common in the lung and thyroid. (12 Dec 1998) |
| malignant giant cell tumour | A type of bone tumour. (12 Dec 1998) |
| giant | 1. A man of extraordinari bulk and stature. "Giants of mighty bone and bold emprise." 2. A person of extraordinary strength or powers, bodily or intellectual. 3. Any animal, plant, or thing, of extraordinary size or power. Giant's Causeway, a vast collection of basaltic pillars, in the county of Antrim on the northern coast of Ireland. Origin: OE. Giant, geant, geaunt, OF. Jaiant, geant, F. Geant, L. Gigas, fr. Gr, from the root of E. Gender, genesis. See Gender, and cf. Gigantic. Like a giant; extraordinary in size, strength, or power; as, giant brothers; a giant son. Giant cell. <anatomy> A very large African heron (Ardeomega goliath). It is the largest heron known. Giant kettle, a pothole of very large dimensions, as found in Norway in connection with glaciers. See Pothole. Giant powder. See Nitroglycerin. <botany> Giant puffball, one of several species of very large squids, belonging to Architeuthis and allied genera. Some are over forty feet long. Source: Websters Dictionary (01 Mar 1998) |
| giant axon | <biology> Extraordinarily large unmyelinated axons found in invertebrates. Some, like the squid giant axon, can approach 1 mm diameter. Large axons have high conduction speeds, the giant axons are invariably involved in panic or escape responses and may (e.g. Crayfish) have electrical synapses to further increase speed. Vertebrate axons with high conduction velocites are much narrower: they are myelinated, allowing saltatory conduction. (17 Dec 1997) |
| giant axonal neuropathy | <paediatrics> A rare disorder beginning at or after the third year of life, and presenting clinically with kinky hair, progressive painless clumsiness, muscle weakness and atrophy, sensory loss, and areflexia. Pathologically, both myelinated and unmyelinated nerve fibres contain axonal spheroids packed with neurofilaments; sporadic in nature. (05 Mar 2000) |
| giant cell | <pathology> A cell of large size, often with many nuclei. They are multinucleated masses produced by the fusion of many cells. They are often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of HIV binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus. (18 Jul 2002) |
| giant cell aortitis | <pathology> Giant cell arteritis involving the aorta. (05 Mar 2000) |
| giant cell arteritis | <pathology> An inflammatory condition of the temporal artery. It is a serious chronic vascular disease, characterised by inflammation of the walls of the blood vessels (vasculitis). The age of affected patients is usually over 50 years of age. It most often involves the carotid artery system, and can lead to blindness or stroke. It can be diagnosed by biopsy of an artery, but there is often a false negative result. Elevation of the erythrocyte sedimentation rate is typical. Treatment is with high dose steroids. Common symptoms include headaches and tenderness over the temple (temporal artery). Can be associated with polymyalgia rheumatica. See: polymyalgia rheumatica. Synonym: cranial arteritis, temporal arteritis (20 Jun 2000) |