| anti-inflammatory agent, non-steroidal | Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain nsaids also may inhibit lipoxygenase enzymes or phospholipase c or may modulate T-cell function. (ama drug evaluations annual, 1994, p 1814-5) (12 Dec 1998) |
|---|---|
| auctorum non | Not of authors. (09 Jan 1998) |
| cancer, lymphoma, non-hodgkin's | A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| carcinoma, non-small-cell lung | A heterogeneous aggregate of at least three distinct histological types of lung cancer, including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. They are dealt with collectively because of the shared properties of poor response to conventional chemotherapy and the potential for cure with surgical resection in a fraction of patients. (12 Dec 1998) |
| Gomori's non-specific acid phosphatase stain | <technique> A method in which formalin-fixed frozen sections are incubated in a substrate containing sodium beta-glycerophosphate and lead nitrate at pH 5.0; the insoluble lead phosphate produced is treated with ammonium sulfide to give a black lead sulfide. (05 Mar 2000) |
| Gomori's non-specific alkaline phosphatase stain | <technique> A calcium-cobalt sulfide method using frozen sections or cold acetone-or formalin-fixed paraffin sections, plus sodium beta-glycerophosphate as a substrate at pH 9.0 to 9.5 with Mg++ as activator; calcium ions precipitate the liberated phosphate, cobalt salt replaces the calcium phosphate, and ammonium sulfide converts the product to a black cobalt sulfide. (05 Mar 2000) |
| chromosomal proteins, non-histone | Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. They bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens. (12 Dec 1998) |
| prescriptions, non-drug | Written directions for the preparation, administration, or application of a non-drug remedy. This includes prescriptions for corrective lenses, self-help and orthopedic devices, and physical therapy and rehabilitation measures. (12 Dec 1998) |
| cytosol non-specific dipeptidase | <enzyme> Also referred to as peptidase a (see synonym to penicillopepsin, EC 3.4.23.20) Registry number: EC 3.4.13.- Synonym: glycyl-l-leucine hydrolase, glycylleucine dipeptidase, gly-leu dipeptide peptidase, dipeptide hydrolase, glycyl-leucine dipeptidase (26 Jun 1999) |
| histiocytosis, non-langerhans-cell | Group of disorders which feature accumulations of active histiocytes and lymphocytes, but where the histiocytes are not langerhans cells. The group includes haemophagocytic lymphohistiocytosis, infection-associated haemophagocytic syndrome, sinus histiocytosis, xanthogranuloma, reticulohistiocytoma, juvenile xanthoma, xanthoma disseminatum, as well as the lipid storage diseases (sea-blue histiocyte syndrome and niemann-pick disease). (12 Dec 1998) |
| nodular non-X histiocytosis | A rare recurring generalised eruption in adults of flesh coloured or erythematous papules remaining localised to the skin and consisting of dermal nodules of mononuclear histiocytes that do not stain for lipid. Synonym: nodular non-X histiocytosis. (05 Mar 2000) |
| non-arcon articulator | An articulator with the equivalent condylar guides attached to the lower member and the hinge axis to the upper member. (05 Mar 2000) |
| non compos mentis | Not of sound mind; mentally incapable of managing one's affairs. Origin: L. Non, not, + compos, participating, competent, + mens, gen. Mentis, mind (05 Mar 2000) |
| non-direct transmission | <epidemiology> A mode of transmission that differs in some mysterious way from indirect transmission. (05 Dec 1998) |
| non-ego | <psychology> The union of being and relation as distinguished from, and contrasted with, the ego. See Ego. Origin: L, not I. Source: Websters Dictionary (01 Mar 1998) |