| lipid granulomatosis | <dermatology, pathology> An accumulation of an excess of lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells in skin lesions. (16 Dec 1997) |
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| lipid histiocytosis | Histiocytosis with cytoplasmic accumulation of lipid, either phospholipid (Niemann-Pick disease) or glucocerebroside (Gaucher's disease). (05 Mar 2000) |
| lipid keratopathy | Occurrence of fats in an area of corneal vascularization. (05 Mar 2000) |
| lipid mobilization | The breakdown of stored triglyceride in adipose tissue with the release of free fatty acids and glycerol. Depot fat hydrolysis is catalyzed by a lipase in response to pituitary lipid mobilization factors (lmf), various hormones, serotonin, or hepatotoxins such as carbon tetrachloride. (12 Dec 1998) |
| lipid-mobilizing hormone | <protein> Polypeptide hormone (_ form: 9894D, 91 residues, _ form has only residues 1-58 of _) from the pituitary hypophysis, that is of particular interest because it is the precursor of endorphins, which are released by proteolysis. Promotes lipolysis and acts through the adenylyl cyclase system. Part of the ACTH group of hormones. (18 Nov 1997) |
| lipid peroxidation | Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor. (12 Dec 1998) |
| lipid peroxides | Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin e, structural separation or low oxygen tension. (12 Dec 1998) |
| lipid pneumonia | Lipoid pneumonia, pulmonary condition marked by inflammatory and fibrotic changes in the lungs due to the inhalation of various oily or fatty substances, particularly liquid petrolatum, or resulting from accumulation in the lungs of endogenous lipid material, either cholesterol from obstructive pneumonitis or following fracture of a bone; phagocytes containing lipid are usually present. Synonym: oil pneumonia. (05 Mar 2000) |
| lipid profile | Pattern of lipids in the blood. (A lipid profile usually includes the total cholesterol, high density lipoprotein (hdl) cholesterol, triglycerides, and the calculated low density lipoprotein (ldl) cholesterol. (12 Dec 1998) |
| lipid storage diseases | A series of disorders due to inborn errors in lipid metabolism resulting in the abnormal accumulation of lipids in the wrong places (examples include gaucher, fabry and niemann-pick diseases and metachromatic leukodystrophy). (12 Dec 1998) |
| acetone compound | <biochemistry> Any of the three compounds created by acetyl coenzyme A (acetoacetate, hydroxybutyrate, and acetone) which are water-soluble cellular fuels normally exported by the liver. They can build up in the blood and body tissues because of starvation, untreated diabetes mellitus, or other disorders that interfere with carbohydrate metabolism. The body rids itself of ketones mainly through urine, but it rids itself of acetone through the lungs, which gives the breath a characteristic fruity odour. If ketones build up in the body long enough, they cause serious illness and coma (see ketoacidosis.) (09 Oct 1997) |
| acyclic compound | An organic compound in which the chain does not form a ring. Synonym: aliphatic compound, open chain compound. (05 Mar 2000) |
| addition compound | Strictly, a complex of two or more complete molecules in which each preserves its fundamental structure and no covalent bonds are made or broken (e.g., hydrates of salts, adducts), loosely, association of acids with basic organic compound's (e.g., amines with HCl), more loosely, addition of two molecules without loss of any atom, but forming new covalent bonds (e.g., CH2==CH2 + Br2 → BrCH2-CH2Br). (05 Mar 2000) |
| aliphatic compound | An organic compound in which the chain does not form a ring. Synonym: aliphatic compound, open chain compound. (05 Mar 2000) |
| APC compound | An analgesic tablet drug combination containing aspirin, phenacetin and caffeine. Very widely used in the 1940's through 1960's; original constituents of popular over-the-counter pain remedies. Use currently much diminished due to concerns about potential renal injury due to the phenacetin. (05 Mar 2000) |