| lipid granulomatosis | <dermatology, pathology> An accumulation of an excess of lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells in skin lesions. (16 Dec 1997) |
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| lipid histiocytosis | Histiocytosis with cytoplasmic accumulation of lipid, either phospholipid (Niemann-Pick disease) or glucocerebroside (Gaucher's disease). (05 Mar 2000) |
| lipid keratopathy | Occurrence of fats in an area of corneal vascularization. (05 Mar 2000) |
| lipid mobilization | The breakdown of stored triglyceride in adipose tissue with the release of free fatty acids and glycerol. Depot fat hydrolysis is catalyzed by a lipase in response to pituitary lipid mobilization factors (lmf), various hormones, serotonin, or hepatotoxins such as carbon tetrachloride. (12 Dec 1998) |
| lipid-mobilizing hormone | <protein> Polypeptide hormone (_ form: 9894D, 91 residues, _ form has only residues 1-58 of _) from the pituitary hypophysis, that is of particular interest because it is the precursor of endorphins, which are released by proteolysis. Promotes lipolysis and acts through the adenylyl cyclase system. Part of the ACTH group of hormones. (18 Nov 1997) |
| lipid peroxidation | Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor. (12 Dec 1998) |
| lipid peroxides | Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin e, structural separation or low oxygen tension. (12 Dec 1998) |
| lipid pneumonia | Lipoid pneumonia, pulmonary condition marked by inflammatory and fibrotic changes in the lungs due to the inhalation of various oily or fatty substances, particularly liquid petrolatum, or resulting from accumulation in the lungs of endogenous lipid material, either cholesterol from obstructive pneumonitis or following fracture of a bone; phagocytes containing lipid are usually present. Synonym: oil pneumonia. (05 Mar 2000) |
| lipid profile | Pattern of lipids in the blood. (A lipid profile usually includes the total cholesterol, high density lipoprotein (hdl) cholesterol, triglycerides, and the calculated low density lipoprotein (ldl) cholesterol. (12 Dec 1998) |
| lipid storage diseases | A series of disorders due to inborn errors in lipid metabolism resulting in the abnormal accumulation of lipids in the wrong places (examples include gaucher, fabry and niemann-pick diseases and metachromatic leukodystrophy). (12 Dec 1998) |
| aberrant complex | An anomalous electrocardiographic complex, more specifically an abnormal ventricular complex caused by abnormal intraventricular conduction of a supraventricular impulse. (05 Mar 2000) |
| activated complex | <chemistry> State of highest energy during a reaction. When reactants form the activated complex, bond breaking and bond formation is occurring. Synonym: transition state. (09 Jan 1998) |
| AIDS dementia complex | <immunology> A frequent cerebral condition in people with AIDS that results in the loss of cognitive capacity, affecting the ability to function in a social or occupational setting. Its cause has not been determined exactly, but may result from HIV infection of cells in the brain or an inflammatory reaction to such infection. (09 Oct 1997) |
| aids-related complex | A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (arc) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of kaposi's sarcoma, signaling the transition to the full-blown aids. (12 Dec 1998) |
| alpha-keto acid dehydrogenase complex | See: alpha-keto acid dehydrogenase. Anaerobic dehydrogenase, an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule (e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenase's, isocitrate dehydrogenase's, and others in EC class 1, excluding those listed under aerobic dehydrogenase. (05 Mar 2000) |