| DNA, complementary | Single-stranded complementary DNA synthesised from an RNA template by the action of RNA-dependent DNA polymerase. Cdna (i.e., complementary DNA, not circular DNA, not c-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe. (12 Dec 1998) |
|---|---|
| anticoding strand | The strand of duplex DNA which is used as a template for the synthesis of mRNA. Synonym: antisense strand. (05 Mar 2000) |
| antiparallel strand | A macromolecular strand that is oriented in the opposite direction of a neighboring strand. (05 Mar 2000) |
| antisense strand | <molecular biology> The strand of DNA which is not used during transcription to make mRNA (anticoding strand). The mRNA made during transcription thus has the same sequence as this strand, so that the eventual protein will be a sense version. (13 Jan 1998) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| viral strand | See: replicative form. (05 Mar 2000) |
| minus strand | See: replicative form. (05 Mar 2000) |
| minus-strand nucleic acid | <molecular biology> An RNA or DNA strand which has the opposite sense of (would be complementary to) the mRNA of a virus. (12 Jan 1998) |
| coding strand | The strand of duplex DNA that has the same sequence as the mRNA (except that mRNA contains ribonucleotides instead of deoxyribonucleotides). Synonym: sense strand. (05 Mar 2000) |
| plus strand | See: replicative form. (05 Mar 2000) |
| positive strand RNA viruses | Class IV and VI viruses that have a single stranded RNA genome that can act as mRNA plus strand) and in which the virus RNA is itself infectious. Includes Picornaviridae, Togaviridae and Retroviridae. (18 Nov 1997) |
| c strand | <molecular biology> An abbreviation for the term complementary strand used of nucleic acids. (18 Nov 1997) |
| sense strand | <molecular biology> The strand of DNA which is used during transcription to make mRNA. The mRNA made thus has the sequence of the antisense strand of DNA, and it codes for a sense strand of polypeptide (which eventually becomes a protein or part of a protein) during translation. (09 Oct 1997) |
| h strand | <molecular biology> The strand of a double-stranded DNA molecule that is more buoyant than the other and floats at the top of a column when the dsDNA is denatured and put in an equilibrium centrifuge. (09 Oct 1997) |
| single-strand break | A break in double-stranded DNA in which only one of the two strands has been cleaved; both strands have not separated from each other. (05 Mar 2000) |