| combinatorial chemistry |
Dr WA Warr Wendy Warr & Associates Cheshire, UK
출처: www.wiley.com/legacy/wileychi/ecc/topic3.html
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| combinatorial chemistry |
The use of chemical methods to generate all possible combinations of chemicals starting with a subset of compounds. The building blocks may be peptides, nucleic acids or small molecules. The libraries of compounds formed by this methodology are used to probe for new pharmaceutical reagents (see high-throughput screening).
출처: falcon.roswellpark.org/labweb/glossary.html
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| combinatorial chemistry |
The use of a small set of chemical building blocks, combined together in multiple ways, using standard chemistries, to create large libraries of medicinally relevant compounds that may be screened for potential new drugs. Combinatorial chemistry is used in tandem with high-throughput screening to identify compounds that bind to a therapeutic target protein and are thus potential new drugs.
출처: www.syrrx.com/technology/glossary.htm
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| combinatorial chemistry |
Preparation of collections of compounds by joining molecular building blocks in different combinations. Also known as combichem.
출처: textonly.kombyonyx.com/glossary.htm
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| combinatorial chemistry |
Is used to synthesize large number of chemical compounds by combining sets of building blocks. Each newly synthesized compound's composition is slightly different from the previous one. A traditional chemist can synthesize 100-200 compounds per year. A combinatorial robotic system can produce in a year thousands or millions compounds which can be tested for potential drug candidates in a high-throughput screening process.
출처: www.bioscreening.com/reference/glossary.htm
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