| gamma globulin | <immunology> A non-specific immunoglobulin (antibody) administered for the purpose of passive immunity. A common example is hepatitis A prophylaxis. (27 Sep 1997) |
|---|---|
| measles immune globulin | A sterile solution of globulin's derived from the blood plasma of normal adult human donors; it is prepared from immune serum globulin that complies with the measles antibody reference standard; a passive immunizing agent. Synonym: measles immunoglobulin. (05 Mar 2000) |
| globulin | <protein> A simple globular protein which cannot be dissolved in pure water but which can be dissolved if a salt is added to the water. It can also be precipitated out of solution and into a solid with a solution of ammonium sulphate at 50% saturation. Examples of globulin proteins are immunoglobulin and cryoglobulin. (14 Oct 1997) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| rho(d) immune globulin | Immunizing agent containing IgG anti-rho(d) used for preventing rh immunization in rh-negative individuals exposed to rh-positive red blood cells. (12 Dec 1998) |
| chickenpox immune globulin | Globulin fraction of serum from persons recently recovered from herpes zoster infection; used to prevent infection of high-risk children. Synonym: chickenpox immunoglobulin. (05 Mar 2000) |
| pertussis immune globulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| plasma accelerator globulin | <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease. Chemical name: Blood-coagulation factor V (12 Dec 1998) |
| poliomyelitis immune globulin | A sterile solution of globulin's that contains those antibodies normally present in adult human blood; it is a passive immunologic agent that attenuates or prevents poliomyelitis, measles, and infectious hepatitis, and confers temporary but significant protection against paralytic polio. Synonym: poliomyelitis immunoglobulin. (05 Mar 2000) |
| corticosteroid-binding globulin | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| progesterone-binding globulin | A glycoprotein migrating as alpha 1-globulin, molecular weight 70,000 to 120,000. The protein, which is present in increased amounts in the plasma during pregnancy, binds mainly progesterone, with other steroids including testosterone competing weakly. (12 Dec 1998) |
| human gamma globulin | A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature. Synonym: human normal immunoglobulin. (05 Mar 2000) |
| serum accelerator globulin | A substance in serum that accelerates the conversion of prothrombin to thrombin in the presence of thromboplastin and calcium; produced by the action of traces of thrombin upon plasma accelerator globulin. (05 Mar 2000) |
| sex hormone-binding globulin | A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Changes in its concentration significantly affect the ratio of unbound (biologically active) testosterone to estradiol in plasma. (12 Dec 1998) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |