| closed reading frame | A sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. Synonym: closed reading frame. (05 Mar 2000) |
|---|---|
| closed skull fracture | Fracture with intact overlying scalp and/or mucous membranes. Synonym: simple skull fracture. (05 Mar 2000) |
| closed surgery | Surgery without incision into skin, e.g., reduction of a fracture or dislocation. (05 Mar 2000) |
| closed system | <biology, ecology> A chemical or biological system that exchanges no matter or energy with the ouside environment. (12 Mar 1998) |
| covalently closed circular DNA | <molecular biology> A circular molecule of double-stranded DNA which is supercoiled, or coiled up on itself due to internal tensions, because there are no breaks in the phosphate backbone (upon which the nucleotide bases are mounted) to relieve the tensions and allow it to form an open circle. (09 Oct 1997) |
| head injuries, closed | Organic or functional damage resulting from trauma to the head where continuity of the scalp and mucous membranes is maintained. When brain injury results from closed head injuries, the primary cause is mechanical stretching and shearing of nerve fibres. Also common are focal intracranial lesions including haematomas and contusions. (12 Dec 1998) |
| semi-closed anaesthesia | Inhalation anaesthesia using a circuit in which a portion of the exhaled air is exhausted from the circuit and a portion is rebreathed following absorption of carbon dioxide. (05 Mar 2000) |
| semi-closed circle | A circuit for administration of an inhalation anaesthetic in which partial rebreathing with carbon dioxide absorption is combined with loss from the circuit of a portion of respired gases through valves. (05 Mar 2000) |
| ecological systems, closed | Systems that provide for the maintenance of life in an isolated living chamber through reutilization of the material available, in particular, by means of a cycle wherein exhaled carbon dioxide, urine, and other waste matter are converted chemically or by photosynthesis into oxygen, water, and food. (12 Dec 1998) |
| fractures, closed | Fractures in which the break in bone is not accompanied by an external wound. (12 Dec 1998) |
| acetyl reduction assay | <investigation> A technique for measuring the nitrogen fixation activity in photosynthetic organisms. It uses a flame ionisation detector and a gas chromatography apparatus to determine the reduction of acetylene to ethylene by the enzyme nitrogenase. (06 May 1997) |
| reduction | <orthopaedics, surgery> The correction of a fracture, dislocation or hernia. (18 Nov 1997) |
| reduction deformity | Congenital absence or attenuation of one or more body parts; usually of the limbs or limb components. (05 Mar 2000) |
| reduction division | The first cell division in meiosis, the process by which germ cells are formed. A unique event in which the chromosome number is reduced from diploid (46 chromosomes) to haploid (23 chromosomes). Also called first meiotic division or first meiosis. (12 Dec 1998) |
| reduction en masse | Reduction of hernial sac and contents, so that intestinal obstruction is still present. (05 Mar 2000) |