| CIS | <abbreviation> Carcinoma in situ. (05 Mar 2000) |
|---|---|
| cis- | 1. <prefix> Prefix meaning on this side, on the near side; opposite of trans-. 2. <genetics> A prefix denoting the location of two or more genes on the same chromosome of a homologous pair, in coupling. 3. <chemistry> A form of geometric isomerism in which similar functional groups are attached on the same side of the plane that includes two adjacent, fixed carbon atoms (e.g., the 2-and 3-OH groups of ribofuranose) in a ring structure. Identical functional groups on the same side of the double bond are cis-. When the four moieties attached to the carbons of the double bond are all different, then the E/Z nomenclature has to be followed. See: entgegen, zusammen. Origin: L. (20 Jun 2000) |
| cis-1,2-dihydrobenzene-1,2-diol dehydrogenase | <enzyme> See also EC 1.3.1.20 (trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; both enzymes catalyze the conversion of benzene dihydrodiol to catechol and may also have hydroxysteroid dehydrogenase activity Chemical name: cis-1,2-dihydroxycyclohexa-3,5-diene (nad) oxidoreductase Registry number: EC 1.3.1.19 Synonym: cis-benzene glycol dehydrogenase, cis-diol dehydrogenase, benzene dihydrodiol dehydrogenase, bedd gene product, nad+-dependent cis-benzene dihydrodiol dehydrogenase, todd gene product (26 Jun 1999) |
| cis-3-chloroacrylic acid dehalogenase | <enzyme> Specific for conversion of cis-3-chloroacrylic acid to muconic saemialdehyde (3-oxopropionic acid); 48 amino-terminal amino acid sequence given in first source Registry number: EC 3.8.1.- Synonym: cis-3caa dehalogenase (26 Jun 1999) |
| cis-9,trans-11-octadecadienoate reductase | <enzyme> Uses NADH and alpha-tocopherol quinol; forms trans-11-octadecenoate Registry number: EC 1.3.1.- Synonym: 9,11-ocdd reductase (26 Jun 1999) |
| cis-aconitic acid | Dehydration product of citric acid; an enzyme-bound intermediate in the tricarboxylic acid cycle. (05 Mar 2000) |
| cis acting | <molecular biology> Having to do with a genetic element (such as a promoter or other regulatory locus) having an effect (like promotion or suppression) on two unrelated targets (such as genes) on the same chromosome as a result of their relative positions on the chromosome. A gene which regulates the transcription into mRNA of other genes nearby on the same chromosome by binding protein transcription factors which are necessary to turn transcription on or off. (09 Oct 1997) |
| cis-acting locus | A section of DNA that affects the activity of DNA sequences on that same molecule of DNA. (05 Mar 2000) |
| cis-acting protein | A protein that acts on the molecule of DNA from which it was expressed. (05 Mar 2000) |
| cis activation | <molecular biology> Activation of a gene by an activator located on the same chromosome i.e. Not by a diffusible product. (18 Nov 1997) |
| cis configuration | <molecular biology> The configuration of an organic molecule containing a double bond between two carbon atoms, where the largest, most complex R groups are on the same side: H H \ / C=C / \ H3C CH3 -OR-The configuration of an organic molecule containing a ring, where the largest, most complex R groups are on the same side: H H | ___ \ / | // \\ [ring viewed edge-on] | \___/ / \ | /---\ H3C CH3 | H3C CH3. A genetics term meaning an event or a gene whose action occurs on the same chromosome. Two mutations in different genes coding for the same phenotype which are on the same chromosome (as opposed to the trans configuration where each homologue has one of the mutations). Compare: trans configuration. (11 Jan 1998) |
| cis-isoprenyltransferase | <enzyme> Cis-isoprene units of dolichyl monophosphate are added to trans,trans-farnesyl pyrophosphate using isopentenyl pyrophosphate as donor; from embryonic rat brain Registry number: EC 2.5.1.- Synonym: long-chain cis-isoprenyltransferase (26 Jun 1999) |
| cis-prenyl transferase | <enzyme> Involved in dolichol biosynthesis Registry number: EC 2.5.1.- Synonym: cis-prenyltransferase (26 Jun 1999) |
| cis-toluene dihydrodiol dehydrogenase | <enzyme> Nad specific dehydrogenase; reduces ring structure Chemical name: 1,2-dihydroxy-3-methylcyclohexa-3,5-diene dehydrogenase Registry number: EC 1.3.- Synonym: ctd dehydrogenase (26 Jun 1999) |
| cis-trans-isomerases | <enzyme> Enzymes that catalyze the rearrangement of geometry about double bonds. Registry number: EC 5.2 (12 Dec 1998) |