| LD | labor and delivery; laboratory data; labyrinthine defect; lactate dehydrogenase; laser Doppler; lear... |
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| cccDNA | covalently closed circular deoxyribonucleic acid |
| cDNA | circular deoxyribonucleic acid; complementary deoxyribonucleic acid |
| CIDS | cellular immunity deficiency syndrome; circular intensity differential scattering; continuous insuli... |
| circ | circuit; circular; circumcision; circumference |
| covalently closed circular DNA | <molecular biology> A circular molecule of double-stranded DNA which is supercoiled, or coiled up on itself due to internal tensions, because there are no breaks in the phosphate backbone (upon which the nucleotide bases are mounted) to relieve the tensions and allow it to form an open circle. (09 Oct 1997) |
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| DNA, circular | Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (12 Dec 1998) |