| ALM | aerial lentiginous melanoma; alveolar living material |
|---|---|
| CMM | cell-mediated mutagenesis; cutaneous malignant melanoma |
| FAMMM | familial atypical multiple mole-melanoma [syndrome] |
| HCMM | hereditary cutaneous malignant melanoma |
| LMM | Lactobacillus maintenance medium; lentigo maligna melanoma; light meromyosin |
| malignant melanoma | <oncology, tumour> A malignant tumour which arises from the pigment producing cells (melanosomes) of the deeper layers of the skin (or the eye). Melanoma is the leading cause of death attributable to skin lesions. Described as an irregular dark skin lesion that may have areas of varying colour. Often greater than 6 mm in diameter. (27 Sep 1997) |
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| malignant melanoma: gallium imaging | <radiology> Greater than50% sensitivity for primary and metastatic sites: 73% sensitivity if lesion is greater than 2 cm, 17% sensitivity if less than 2 cm, see: gallium: indications malignant melanoma (12 Dec 1998) |
| malignant melanoma in situ | A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of malignant melanoma in situ. (05 Mar 2000) |
| malignant melanoma: staging | <radiology> Clark staging: level I: all tumour cells above basement membrane (in situ), level II: tumour extends to papillary dermis, level III: tumour extends to interface between papillary and reticular dermis, level IV: tumour extends between bundles of collagen of reticular dermis, level V: tumour invasion of sucutaneous tissue (87% metastases) Breslow staging: thin: less than 0.75 mm depth of invasion, intermediate: 0.76 - 3.99 mm depth of invasion, thick: greater than 4 mm depth of invasion see: malignant melanoma (12 Dec 1998) |
| melanoma | <oncology, tumour> A tumour arising from the melanocytic system of the skin and other organs. When used alone the term refers to malignant melanoma. (18 Nov 1997) |
| melanoma, amelanotic | An unpigmented malignant melanoma. It is an anaplastic melanoma consisting of cells derived from melanoblasts but not forming melanin. (12 Dec 1998) |
| melanoma growth stimulatory activity | Cytokine of the C X C subfamily. Potent mitogen. Activates and is chemotactic for, neutrophils. (18 Nov 1997) |
| minimal deviation melanoma | <dermatology, tumour> A malignant melanoma showing less cytologic atypia than is usual in melanoma cells showing asymmetric expansile invasion of the dermis. (05 Mar 2000) |
| Cloudman melanoma | <tumour> A transplantable melanoma that arose spontaneously in a mouse of DBA strain, and which grows and metastasizes in mice of related strains. (05 Mar 2000) |
| halo melanoma | <tumour> A rare condition in which a melanoma is surrounded by an irregular area of depigmentation. (05 Mar 2000) |
| Harding-Passey melanoma | <tumour> A melanin-forming tumour that arose spontaneously in a non-inbred mouse, and that is transplantable to mice of many strains but does not ordinarily metastasize. (05 Mar 2000) |
| Xiphophorus melanoma receptor kinase | <enzyme> Growth factor receptor protein with an extracellular ligand binding domain and an intracellular catalytic domain Registry number: EC 2.7.1.- Synonym: xmrk protein (26 Jun 1999) |
| nodular melanoma | <tumour> Primary cutaneous melanoma characterised by dermal invasion extending to the lateral margins of epidermal involvement or ulceration. (05 Mar 2000) |
| subungual melanoma | <tumour> A melanoma beginning in the skin at the border of or beneath the nail. Synonym: melanotic whitlow. (05 Mar 2000) |
| superficial spreading melanoma | <tumour> Primary cutaneous melanoma characterised by intraepidermal growth extending laterally beyond the site of dermal invasion. (05 Mar 2000) |