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progressive choroidal atrophy An x chromosome-linked abnormality characterised by atrophy of the choroid and degeneration of the retinal pigment epithelium causing night blindness.
(12 Dec 1998)
acral lentiginous melanoma <tumour> A form of malignant lentigo melanoma that occurs in acral areas not excessively exposed to sunlight and where hair follicles are absent.
(05 Mar 2000)
amelanotic melanoma <tumour> An anaplastic melanoma consisting of cells derived from melanocytes but not forming melanin.
(05 Mar 2000)
benign juvenile melanoma A benign, slightly pigmented or red superficial small skin tumour composed of spindle-shaped, epithelioid, and multinucleated cells that may appear atypical; most common in children, but also appearing in adults.
Synonym: benign juvenile melanoma, epithelioid cell nevus, spindle cell nevus.
(05 Mar 2000)
cancer, melanoma A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. It can be cured if detected early, before spread (metastasis) to other areas. Diagnosis is confirmed by a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma.
(12 Dec 1998)
melanoma <oncology, tumour> A tumour arising from the melanocytic system of the skin and other organs. When used alone the term refers to malignant melanoma.
(18 Nov 1997)
melanoma, amelanotic An unpigmented malignant melanoma. It is an anaplastic melanoma consisting of cells derived from melanoblasts but not forming melanin.
(12 Dec 1998)
melanoma growth stimulatory activity Cytokine of the C X C subfamily. Potent mitogen. Activates and is chemotactic for, neutrophils.
(18 Nov 1997)
minimal deviation melanoma <dermatology, tumour> A malignant melanoma showing less cytologic atypia than is usual in melanoma cells showing asymmetric expansile invasion of the dermis.
(05 Mar 2000)
Cloudman melanoma <tumour> A transplantable melanoma that arose spontaneously in a mouse of DBA strain, and which grows and metastasizes in mice of related strains.
(05 Mar 2000)
halo melanoma <tumour> A rare condition in which a melanoma is surrounded by an irregular area of depigmentation.
(05 Mar 2000)
Harding-Passey melanoma <tumour> A melanin-forming tumour that arose spontaneously in a non-inbred mouse, and that is transplantable to mice of many strains but does not ordinarily metastasize.
(05 Mar 2000)
Xiphophorus melanoma receptor kinase <enzyme> Growth factor receptor protein with an extracellular ligand binding domain and an intracellular catalytic domain
Registry number: EC 2.7.1.-
Synonym: xmrk protein
(26 Jun 1999)
nodular melanoma <tumour> Primary cutaneous melanoma characterised by dermal invasion extending to the lateral margins of epidermal involvement or ulceration.
(05 Mar 2000)
subungual melanoma <tumour> A melanoma beginning in the skin at the border of or beneath the nail.
Synonym: melanotic whitlow.
(05 Mar 2000)
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