| MAD | Major Antigenic Determinant |
|---|---|
| MHC | Major Histocompatibility Complex |
| EMM | erythema multiforme major |
| HMC | hand-mirror cell; health maintenance cooperative; heroin, morphine, and cocaine; histocompatibility ... |
| MAC | MacConkey [broth]; major ambulatory category; malignancy-associated changes; maximum allowable conce... |
| posthemiplegic chorea | A unilateral athetosis involving hemiplegic limbs, usually seen in children. Synonym: posthemiplegic chorea. (05 Mar 2000) |
|---|---|
| saltatory chorea | Rhythmic dancing movements, as in procursive chorea. (05 Mar 2000) |
| procursive chorea | A form in which the patient whirls around, runs forward, or exercises a sort of rhythmic dancing movement. Synonym: dancing chorea. (05 Mar 2000) |
| hemilateral chorea | Chorea involving the muscles on one side only. Synonym: chorea dimidiata, hemilateral chorea. (05 Mar 2000) |
| Henoch's chorea | A disorder in which sudden spasmodic coordinated movements of certain muscles or groups of physiologically related muscles occur at irregular intervals. Synonym: Henoch's chorea. (05 Mar 2000) |
| hereditary chorea | A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic. Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease. (05 Mar 2000) |
| senile chorea | A disorder resembling Sydenham's chorea, not associated with cardiac disease or dementia, occurring in the aged. (05 Mar 2000) |
| Huntington chorea | <neurology> An inherited adult-onset disease of the central nervous system. It is characterised by dementia and bizarre involuntary movements. The disease is progressive and there is currently no known cure. The identification of the gene (huntingtin) on chromosome 4p now allows for direct mutation analysis. The gene contains a trinucleotide repeat (CAG) that is found to be expanded in length in affected patients. The normal allele size ranges from 11 to 34 triplet repeat units, while 42 repeats or greater is considered diagnostic of Huntington disease. As in other trinucleotide repeat disorders, the phenomenom of anticipation has been observed, in this case expressed as earlier age of onset in offspring, particularly with paternal transmission. A further complication is the presence of two neighboring trinucleotide repeats (both CCG) which can expand independently without causing the disease. Early PCR primer sets encompassed these adjacent repeats, potentially yielding false positive test results, newer primers hone in more closely on the CAG repeat sequence. Careful attention must be paid to the psychosocial support structure of prospective test subjects in Huntington disease genetic counseling. Established protocols require systematic neuropsychiatric assessment and informed consent prior to DNA testing. Inheritance: autosomal dominant. (29 Dec 1997) |
| Huntington's chorea | A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic. Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease. (05 Mar 2000) |
| hysterical chorea | Conversion hysteria in which involuntary, quick, and purposeless (choreiform) movements constitute the chief feature. (05 Mar 2000) |
| dancing chorea | A form in which the patient whirls around, runs forward, or exercises a sort of rhythmic dancing movement. Synonym: dancing chorea. (05 Mar 2000) |
| degenerative chorea | A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic. Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease. (05 Mar 2000) |
| Sydenham's chorea | A postinfectious chorea appearing several months after a streptococcal infection with subsequent rheumatic fever. The chorea typically involves the distal limbs and is associated with hypotonia and emotional lability. Improvement occurs over weeks or months and exacerbations occur without associated infection recurrence. Synonym: acute chorea, chorea minor, chorea, juvenile chorea, rheumatic chorea, Sydenham's disease. (05 Mar 2000) |
| electric chorea | Progressively fatal spasmodic disorder, possibly of malarial origin, occurring chiefly in Italy, a severe form of Sydenham's chorea, in which the spasms are rapid and of a specially jerky character. (05 Mar 2000) |
| juvenile chorea | A postinfectious chorea appearing several months after a streptococcal infection with subsequent rheumatic fever. The chorea typically involves the distal limbs and is associated with hypotonia and emotional lability. Improvement occurs over weeks or months and exacerbations occur without associated infection recurrence. Synonym: acute chorea, chorea minor, chorea, juvenile chorea, rheumatic chorea, Sydenham's disease. (05 Mar 2000) |