| immunization, chickenpox | This vaccine prevents the common disease known as chickenpox (varicella zoster). While chickenpox is often considered a trivial illness, it can cause significant lost time on the job and in school and have serious complications including ear infections, pneumonia, and infection of the rash with bacteria, inflammation of the brain (encephalitis) leading to difficulty with balance and coordination (cerebellar ataxia), damaged nerves (palsies), and reye's syndrome, a potentially fatal complication. The vaccination requires only one shot given at about a year of age. If an older person has not had chickenpox, the shot may be given at any time. There have been few significant reactions to the chickenpox vaccine. All children, except those with a compromised immune system, should have the vaccination. (12 Dec 1998) |
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| accelerator globulin | Globulin in serum that promotes the conversion of prothrombin to thrombin in the presence of thromboplastin and ionised calcium. See: factor Va, factor V, serum accelerator globulin. (05 Mar 2000) |
| albumin-globulin ratio | The ratio of albumin to globulin in the serum or in the urine in kidney disease; the normal ratio in the serum is approximately 1.55. (05 Mar 2000) |
| alpha-globulin | <protein> The serum globulins with the most rapid electrophoretic migration, further subdivided into faster alpha(1)- and slower alpha(2)-globulins. (12 Dec 1998) |
| antihemophilic globulin | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin A | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin B | <chemical> Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, ixa, forms a complex with factor viii and calcium on platelet factor 3 to activate factor x to xa. Deficiency of factor ix results in christmas disease (haemophilia b). Chemical name: Blood-coagulation factor IX (12 Dec 1998) |
| antihuman globulin | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| antilymphocyte globulin | <protein> Antibodies which attach to and destroy lymphocytes. This may be used clinically by injection into a vein, for example in aplastic anaemia. (13 Nov 1997) |
| b1C globulin | The third component (C3) of complement. See: component of complement. (05 Mar 2000) |
| b1E globulin | The fourth component (C4) of complement. See: component of complement. (05 Mar 2000) |
| b1F globulin | The fifth component (C5) of complement. See: component of complement. (05 Mar 2000) |
| gamma globulin | <immunology> A non-specific immunoglobulin (antibody) administered for the purpose of passive immunity. A common example is hepatitis A prophylaxis. (27 Sep 1997) |
| globulin | <protein> A simple globular protein which cannot be dissolved in pure water but which can be dissolved if a salt is added to the water. It can also be precipitated out of solution and into a solid with a solution of ammonium sulphate at 50% saturation. Examples of globulin proteins are immunoglobulin and cryoglobulin. (14 Oct 1997) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |