| SCD | scleroderma; service-connected disability; sickle-cell disease; spinocerebellar degeneration; subacu... |
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| amidoPRT | amido-Phospho-Ribosyl-Transferase |
| APRT | Adenine Phospho-Ribosyl-Transferase |
| COMT | Catechol-O-Methyl Transferase |
| GGT | 1) Gamma(γ)-Glutamyl Transpeptidase 2) Gamma(γ)-Glutamyl Transferase |
| l-carnitine | <amino acid> Is a dipeptide - an amino acid made from two other aminos, methionine and lysine. It can be synthesised in the liver if sufficient amounts of lysine, B1, B6 and iron are available. Muscle and organ meat, fish and milk products are the best sources of carnitine in the diet. Carnitine has been shown to have a major role in the metabolism of fat and in the reduction of triglycerides by increasing fat utilisation. It transfers fatty acids across the membranes of the mitochondria where they can be utilised as sources of energy. It also increases the rate at which the liver uses fats. By preventing fatty build-up, this amino acid aids in weight loss and decreases the risk of heart disease. Carnitine has been shown to be deficient in hearts of patients who have died of acute myocardial infections. Muscular dystrophy and myotonic dystrophy have been shown to lead to carnitine loss in the urine and therefore higher requirements for it. Carnitine is stored primarily in the skeletal muscles and heart, where it is needed to transform fatty acids into energy for muscular activity. It is also concentrated in sperm and the brain. Many athletes have noted increased endurance and muscle building with carnitine supplementation. Deficiencies may increase symptoms of fatigue, angina, muscle weakness or confusion. A low level of Vitamin C will also result in apparent Carnitine deficiency. It is contraindicated for people with liver or kidney disease or diabetes It has proven helpful in improving lipid metabolism and reducing elevated total lipids, cholesterol and triglycerides in people with cardiac problems and diabetes, but should only be taken with medical supervision in these conditions. (25 Jun 1999) |
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| acetate-succinate CoA-transferase | <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA Registry number: EC 2.8.3.- Synonym: acetate-succinate coenzyme a-transferase (26 Jun 1999) |
| acyl-CoA transferase | <enzyme> Transfers CoA from succinyl-CoA to propionate, forming propionyl-CoA plus succinate Registry number: EC 2.8.3.- Synonym: propionate CoA-transferase, acyl-coenzyme a transferase (26 Jun 1999) |
| alpha2-8-KDN-transferase | <enzyme> Catalyses the transfer of deaminated neuraminic acid, kdn (2-keto-3-deoxy-d-glycero-d-galacto-nononic acid) from cmp-kdn to the non-reducing termini of oligo-polysialyl chains of polysialoglycoprotein Registry number: EC 2.4.99.- Synonym: kdn-transferase (26 Jun 1999) |
| arabinosyl-hydroxyproline transferase | <enzyme> Involved in glycoprotein synthesis in plants Registry number: EC 2.4.2.- Synonym: ar-hpt, protein-arabinosyltransferase (26 Jun 1999) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase | <enzyme> With EC 2.4.1.148 this is called beta6-glcnac-transferase b Registry number: EC 2.4.1.102 Synonym: gal3-galnac-mucin-6-glcnac transferase, udp-glcnac-gal1-3galnac-r-(glcnac to galnac)-beta1-6glcnac transferase, core 2 glcnac transferase, core 2-n-acetylglucosaminyltransferase, core 2 beta6-gn-t (26 Jun 1999) |
| butyryl-CoA acetoacetate CoA transferase | <enzyme> Butyryl-CoA + acetoacetate yields butyrate + acetoacetyl-CoA Registry number: EC 2.8.3.- Synonym: butyryl-coenzyme a acetoacetate coenzyme a transferase (26 Jun 1999) |
| p21(ras) farnesyl-protein transferase | <enzyme> Transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit Registry number: EC 2.5.1.- Synonym: farnesyl-protein transferase p21(ras), ras p21 farnesyl-protein transferase, protein-cysteine farnesyltransferase, pc farnesyltransferase, protein farnesyltransferase, p21(ras) farnesyltransferase, farnesyl-protein transferase-alpha, farnesyl-protein transferase-beta, ft alpha, ft beta, caax farnesyltransferase, ftase enzyme (26 Jun 1999) |
| galactosyl transferase | <enzyme> Enzyme catalysing the transfer of galactose units from the sugar nucleotide, uridine diphospho galactose UDP galactose) to an acceptor, commonly N acetyl glucosamine in a glycan chain, forming a glycosidic bond involving C1 of galactose. (18 Nov 1997) |
| glutathione S-transferase | A class of enzymes that catalyze the reaction of glutathione with an acceptor molecule (e.g., an arene oxide) to form an S-substituted glutathione; a key step in detoxification of many substances; start of the mercapturic acid pathway. Synonym: ligandin. (05 Mar 2000) |
| glutathione transferase | <enzyme> A transferase that catalyses the addition of aliphatic, aromatic, or heterocyclic radicals as well as epoxides and arene oxides to glutathione. Addition takes place at the sulfur atom. It also catalyses the reduction of polyol nitrate by glutathione to polyol and nitrite. Chemical name: RX:glutathione R-transferase Registry number: EC 2.5.1.18 (12 Dec 1998) |
| glycoprotein hormone-specific N-acetylgalactosamine transferase | <enzyme> Transfers galnac to the terminal glcnac moieties of glcnac2man3glcnac2asn Registry number: EC 2.4.1.- Synonym: ghs-acgalnh2 transferase, glycoprotein hormone galnac transferase, glycoprotein hormone - n-acetylgalactosaminyltransferase (26 Jun 1999) |
| glycylpeptide-N-myristoyl transferase | <enzyme> From yeast; absolutely specific for attachment of myristic acid to amino-terminal glycine residues of proteins Registry number: EC 2.3.1.97 Synonym: n-myristoyltransferase, myristoyl CoA-glycylpeptide-n-myristoyltransferase, myristoyl CoA-protein n-myristoyltransferase, myristoyl coenzyme a-protein n-myristoyltransferase, glycylpeptide-n-myristoyltransferase, protein n-myristoyl transferase (26 Jun 1999) |
| PEP-UDP-GlcNAc transferase | <enzyme> Forms udp-n-acetylglucosaminyl-enolpyruvate Registry number: EC 2.4.1.- Synonym: phosphoenolpyruvate-udp-n-acetylglucosaminyltransferase, pep-udp-glcnac-enolpyruvate transferase (26 Jun 1999) |