| nonsuppressible insulin-like activity | A blood protein (nsila) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of cohn fraction III, 10% of the activity is found in the supernatant (nsila-s) and the remaining activity in the precipitate (nsila-p). The latter is a large molecular compound, much less stable than the soluble fraction. Nsila-s is a more potent growth factor than insulin and exhibits sulfation activity. (12 Dec 1998) |
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| drug activity | A measure of the physiological response a drug produces. A less active drug produces less response (and visa versa). (12 Dec 1998) |
| insulin-like activity | A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin. (05 Mar 2000) |
| intrinsic sympathomimetic activity | The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system. (05 Mar 2000) |
| optical activity | The ability of a material to rotate the plane of polarized light. (09 Oct 1997) |
| triggered activity | One or a series of spontaneously generated heart beats originating from an action potential that produces an after-depolarisation which reaches activation threshold. (05 Mar 2000) |
| unit of thyrotrophic activity | The activity of an amount of an extract of the anterior lobe of the hypophysis which, given daily for 5 days, will cause the thyroid of a guinea pig (weighing 200 g) to reach a weight of 600 mg. (05 Mar 2000) |
| zone of polarizing activity | <cell biology> The small group of mesenchyme cells in avian limb buds that is located at the posterior margin of the developing bud and that produces a substance, possibly retinoic acid, that provides positional information to the developing limb bud. (18 Nov 1997) |
| active caries | Microbial-induced lesions of teeth that are increasing in size. (05 Mar 2000) |
| arrested dental caries | Carious lesions that have become inactive and stopped progressing; they may exhibit changes in colour and/or consistency. (05 Mar 2000) |
| buccal caries | Caries beginning with decay on the buccal surface of a tooth. (05 Mar 2000) |
| caries | 1. <pathology> The molecular decay or death of a bone, in which it becomes softened, discoloured and porous. It produces a chronic inflammation of the periosteum and surrounding tissues and forms a cold abscess filled with a cheesy, fetid, puslike liquid, which generally burrows through the soft parts until it opens externally by a sinus or fistula. 2. <dentistry> Another name for cavities due to tooth decay, dental caries. (18 Nov 1997) |
| radiation caries | Caries of the cervical regions of the teeth, incisal edges, and cusp tips secondary to xerostomia induced by radiation therapy to the head and neck. (05 Mar 2000) |
| recurrent caries | Caries recurring in an area due to inadequate removal of the initial decay, usually beneath a restoration or new decay at a site where caries has previously occurred. (05 Mar 2000) |
| cemental caries | <dentistry> Caries of the cementum of a tooth. (05 Mar 2000) |