| CCB | calcium channel blocker |
|---|---|
| DHPCCB | dihydropyridine calcium channel blocker |
| NDHPCCB | non-dihydropyridine calcium channel blocker |
| TC | target cell; taurocholate; temperature compensation; teratocarcinoma; tertiary cleavage; tetracyclin... |
| VOCC | voltage-operated calcium channel |
| alpha blocking | The attenuation of the occipital alpha rhythm (8-14 Hz brain waves as seen on an electroencephalogram), produced by opening the eyes or by intense mental concentration. (05 Mar 2000) |
|---|---|
| antibodies, blocking | Antibodies that inhibit the reaction between antigen and other antibodies or sensitised T-lymphocytes (e.g., antibodies of the IgG class that compete with IgE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumours and prevent destruction of tumour cells by cytotoxic T-lymphocytes have also been called enhancing antibodies. (12 Dec 1998) |
| blocking | 1. Obstructing; arresting of passage, conduction, or transmission. 2. In psychoanalysis, a sudden break in free association occurring when a painful subject or repressed complex is touched. 3. Sudden cessation of thoughts and speech, which may indicate the presence of a severe thought disorder or a psychosis. (05 Mar 2000) |
| blocking activity | The repression or elimination of electrical activity in the brain by the arrival of a sensory stimulus. (05 Mar 2000) |
| blocking antibody | An antibody used in a reaction to prevent some other reaction taking place, for example one antibody competing with another for a cell surface receptor. See: desensitisation. (18 Nov 1997) |
| Rh blocking test | A test for nonagglutinating Rh antibodies: an Rh agglutination test is first carried out; if the test for Rh agglutinins is negative, then 1 drop of anti-Rho agglutinating serum of moderate titre is mixed with the patient's serum containing Rh-positive test cells; if after incubating for from 1 to 2 hr at 37캜 no agglutination occurs, Rho-blocking antibodies are assumed to be present in the patient's serum. (05 Mar 2000) |
| spermatogenesis-blocking agents | Chemical substances which inhibit the process of spermatozoa formation at either the first stage, in which spermatogonia develop into spermatocytes and then into spermatids, or the second stage, in which spermatids transform into spermatozoa. (12 Dec 1998) |
| neuromuscular blocking agents | Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (neuromuscular nondepolarising agents) or noncompetitive, depolarising agents (neuromuscular depolarising agents). Both prevent acetylcholine from triggering the muscle contraction and they are used as anaesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. (12 Dec 1998) |
| gated ion channel | <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases. (05 May 1997) |
| voltage-gated channel | A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes. (05 Mar 2000) |
| voltage gated ion channel | <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction. See: sodium channel. (18 Nov 1997) |
| channel | A furrow, gutter, or groovelike passageway. See: canal. Origin: L. Canalis (05 Mar 2000) |
| channel forming ionophore | <chemistry> An ionophore that makes an amphipathic pore with hydrophobic exterior and hydrophilic interior. most known types are cation selective. (18 Nov 1997) |
| channel gating | <physiology> Small currents in the membrane just prior to the increase in ionic permeability, due to the movement of charged particles within the membrane. So called because they open the gates for current flow through ion channels. (20 Mar 1998) |
| channel islands | A group of four british islands and several islets in the english channel off the coast of france. They are known to have been occupied prehistorically. They were a part of normandy in 933 but were united to the british crown at the time of the norman conquest in 1066. Guernsey and jersey originated noted breeds of cattle. (12 Dec 1998) |