| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| 영문 | solid tumor | 한글 | 고형종양 |
|---|---|---|---|
| 설명 | 세포로 꽉 찬 종양을 말함. 백혈병 등의 혈액암과 같이 형태를 취하지 않고 액체인 상태의 암과 대조되는 용어로서 단단한 덩어리로 구성된 악성종양이다. 대부분의 종양이 이에 해당한다. 특히 표피조직에서 기원한 종양을 말한다. |
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| 영문 | ulcerating tumor | 한글 | 궤양성 종양 |
|---|---|---|---|
| 설명 | 종양의 표면에 궤양이 발생하는 것. 대개, 매우 빨리 자라는 종양에서 혈류 공급이 종양세포의 자라는 속도를 감당하지 못해 종양중심부 조직이 괴사에 빠져 궤양을 형성하는 경우가 많다. 육안으로 보면 빨갛고, 열이나며, 지저분해 보인다. |
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| 영문 | epithelial tumor | 한글 | 상피성종양 |
|---|---|---|---|
| 설명 | 정상 사람의 조직은 체표면을 덮는 역할을 하는 조직과, 주로 발생기의 중배엽에서 분화한 간엽조직에서 유래하는 결합조직, 뼈, 연골, 지방, 근육, 혈관 등의 조직의 두 계통으로 나눌 수 있다. 전자를 상피성 조직, 후자를 비상피성 조직이라 하며 그 각각을 구성하는 세포를 상피성 세포, 비상피세포라 총칭한다. 상피성 세포에서 기원하는 종양이 상피성 종양이며, 근처의 조직으로 침투나 혈류, 림프의 조직을 타고 원거리의 장기로 이동하지 않는 양성종양에는 선종, 유두종 등이 있고 양성과 반대로 근처의 조직으로 침투, 원격장기로 전이하는 악성종양을 모두 통칭하여 암종(carcinoma)이라고 한다. |
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| 영문 | medullary tumor | 한글 | 수질성 종양 |
|---|---|---|---|
| 설명 | 암의 병리학적인 분류중 하나. 여러 기관의 암에서 나타나는데 주로 갑상샘암이나 유방암에서 보인다. |
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| BBB | 1) Bundle Branch Block 2) Blood Brain Barrier - Blood Brain Barrier |
|---|---|
| ABS | abdominal surgery; acute brain syndrome; Adaptive Behavior Scale; admitting blood sugar; adult bovin... |
| MBD | Marchiafava-Bignami disease; Mental Deterioration Battery; methylene blue dye; minimal brain damage;... |
| BTCG | Brain Tumor Cooperative Group |
| BTSG | Brain Tumor Study Group |
| brain cicatrix | A scarring of the brain resulting from injury (reactive gliosis), characterised by proliferation of mesodermal (vascular) and ectodermal (glial) elements. See: isomorphous gliosis. (05 Mar 2000) |
|---|---|
| brain concussion | Transient or prolonged unconsciousness with or without impairment of higher mental functions and/or brainstem functions, due to a violent blow to the head. (12 Dec 1998) |
| brain congestion | Increased volume of the intravascular compartment of the brain; often associated with brain swelling. Synonym: encephalaemia. (05 Mar 2000) |
| brain contusion | A head injury of sufficient force to bruise the brain. The bruising of the brain will often involve the surface of the brain and cause an extravasation of blood without rupture of the pia-arachnoid. Often associated with a concussion. (27 Sep 1997) |
| brain death | Total cessation of brain function for 24 hours as manifested by absence of spontaneous movement, absence of spontaneous respiration, and absence of all brainstem reflexes. (12 Dec 1998) |
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain diseases, metabolic | Metabolic disorders which lead to pathological changes and/or functional deviations of the brain. (12 Dec 1998) |
| brain-heart infusion agar | A medium used for the isolation of fastidious microorganisms, especially fungi. (05 Mar 2000) |
| brain herniation | A condition that occurs when the brain is under abnormally increased pressure. The increased intracranial pressure forces the brain downward inside the skull. This results in typical neurologic manifestations (coma, paralysis and a unilateral dilated pupil). May occur secondary to head injury, primary or metastatic brain tumour, bacterial meningitis and brain abscess. Brain herniations may involve different portions of the brain such as the cerebellum (cerebellar herniation), uncus (uncal herniation) and transtentorial herniation of the cerebrum. (27 Sep 1997) |
| brain injury | Acute injuries to the brain, general or unspecified. (12 Dec 1998) |
| brain iron | <radiology> Normal, Infant: NONE, Adult: globus pallidum, substantia nigra, red nucleus, dentate nucleus, Aging: (adult) and putamen, Degenerative disease, Parkinson disease: putamen, SN compacta, Huntington disease: caudate, putamen, Alzheimer disease: cerebral cortex, Hallervorden-Spatz disease, MS: thalamus, putamen, Others, AVM: malformation and rim, Bleed: rim macrophages, Haemorrhagic CVA: gyral / basal ganglia MRI: low T1 and T2 signal (12 Dec 1998) |
| brain laceration | Gross tearing of neural tissue. (05 Mar 2000) |
| brain lipid | Impure cephalin possessing marked haemostatic action when locally applied. (05 Mar 2000) |
| brain mantle | Origin: L. See Pall the garment. 1. A large, square, woolen cloak which enveloped the whole person, worn by the Greeks and by certain Romans. It is the Roman name of a Greek garment. 2. A band of white wool, worn on the shoulders, with four purple crosses worked on it; a pall. The wool is obtained from two lambs brought to the basilica of St. Agnes, Rome, and blessed. It is worn by the pope, and sent to patriarchs, primates, and archbishops, as a sign that they share in the plenitude of the episcopal office. Befoer it is sent, the pallium is laid on the tomb of St. Peter, where it remains all night. 3. <zoology> The mantle of a bivalve. See Mantle. The mantle of a bird. Source: Websters Dictionary (01 Mar 1998) |