| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| 영문 | testicular feminization syndrome | 한글 | 고환여성화증후군 |
|---|---|---|---|
| 설명 | 이차성장을 포함하여, 외성기의 발육은 여성이지만 고환이 존재하고, 자궁과 자궁관이 결핍되어 있는 남성 거짓남녀한몸증의 극단적 형태이다. 이것은 테스토스테론의 작용에 대한 말단기관의 저항에 기인한다. |
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| 영문 | irritable bowel syndrome | 한글 | 과민성대장증후군 |
|---|---|---|---|
| 설명 | 배변장애, 복통, 복부팽만 등의 증상이 있으나 기질적인 병변이 없음이 확인된 예를 총망라한 임상 증후군이다. 가장 흔한 소화기 질환이며(전소화기 환자의 70~80%) 가장 흔한 질병(전체 인구의 약 20%)이다. 여성이 남성에 비해 2배 정도 많이 발생하며 30대 및 40대에서 호발하고 선진 공업국에서 많이 발생한다. 진단을 위해서는 병력 청취가 가장 중요하고 각종 검사로서 기질병을 제외해야 한다. 치료로는 안정요법(정신과적 면담 및 심리요법, 신경안정제), 식사요법(고섬유질 음식 섭취, 자극성 음식 피하기), 약물 요법(창자경련 진정제, 변비 완화제, 지사제) 등을 사용한다. |
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| 영문 | withdrawal syndrome | 한글 | 금단증후근 |
|---|---|---|---|
| 설명 | 알코올, 마약, 바비투르산계 최면약 등의 약물을 장기간 복용하여 약물이 없이는 견딜 수 없게된 뒤, 그 약물을 중지한 경우에 나타나는, 고통이 수반되는 신체적 증상을 말한다. 연속 복용의 기간에 따라 증상이 무거워진다. 통상적으로 구토, 설사, 혈압상승, 빠른맥, 땀남, 혼수 등의 증상이 나타난다. |
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| BBB | 1) Bundle Branch Block 2) Blood Brain Barrier - Blood Brain Barrier |
|---|---|
| MBD | Marchiafava-Bignami disease; Mental Deterioration Battery; methylene blue dye; minimal brain damage;... |
| CBS | cervicobrachial syndrome; chronic brain syndrome; clinical behavioral science; conjugated bile salts... |
| NBS | N-bromosuccinimide; National Bureau of Standards; neuroblastoma supressor; nevoid basal cell carcino... |
| PPS | Personal Preference Scale; physician, patient and society [course]; polyvalent pneumococcal polysacc... |
| brain congestion | Increased volume of the intravascular compartment of the brain; often associated with brain swelling. Synonym: encephalaemia. (05 Mar 2000) |
|---|---|
| brain contusion | A head injury of sufficient force to bruise the brain. The bruising of the brain will often involve the surface of the brain and cause an extravasation of blood without rupture of the pia-arachnoid. Often associated with a concussion. (27 Sep 1997) |
| brain death | Total cessation of brain function for 24 hours as manifested by absence of spontaneous movement, absence of spontaneous respiration, and absence of all brainstem reflexes. (12 Dec 1998) |
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain diseases, metabolic | Metabolic disorders which lead to pathological changes and/or functional deviations of the brain. (12 Dec 1998) |
| brain-heart infusion agar | A medium used for the isolation of fastidious microorganisms, especially fungi. (05 Mar 2000) |
| brain herniation | A condition that occurs when the brain is under abnormally increased pressure. The increased intracranial pressure forces the brain downward inside the skull. This results in typical neurologic manifestations (coma, paralysis and a unilateral dilated pupil). May occur secondary to head injury, primary or metastatic brain tumour, bacterial meningitis and brain abscess. Brain herniations may involve different portions of the brain such as the cerebellum (cerebellar herniation), uncus (uncal herniation) and transtentorial herniation of the cerebrum. (27 Sep 1997) |
| brain injury | Acute injuries to the brain, general or unspecified. (12 Dec 1998) |
| brain iron | <radiology> Normal, Infant: NONE, Adult: globus pallidum, substantia nigra, red nucleus, dentate nucleus, Aging: (adult) and putamen, Degenerative disease, Parkinson disease: putamen, SN compacta, Huntington disease: caudate, putamen, Alzheimer disease: cerebral cortex, Hallervorden-Spatz disease, MS: thalamus, putamen, Others, AVM: malformation and rim, Bleed: rim macrophages, Haemorrhagic CVA: gyral / basal ganglia MRI: low T1 and T2 signal (12 Dec 1998) |
| brain laceration | Gross tearing of neural tissue. (05 Mar 2000) |
| brain lipid | Impure cephalin possessing marked haemostatic action when locally applied. (05 Mar 2000) |
| brain mantle | Origin: L. See Pall the garment. 1. A large, square, woolen cloak which enveloped the whole person, worn by the Greeks and by certain Romans. It is the Roman name of a Greek garment. 2. A band of white wool, worn on the shoulders, with four purple crosses worked on it; a pall. The wool is obtained from two lambs brought to the basilica of St. Agnes, Rome, and blessed. It is worn by the pope, and sent to patriarchs, primates, and archbishops, as a sign that they share in the plenitude of the episcopal office. Befoer it is sent, the pallium is laid on the tomb of St. Peter, where it remains all night. 3. <zoology> The mantle of a bivalve. See Mantle. The mantle of a bird. Source: Websters Dictionary (01 Mar 1998) |
| brain metastases | <oncology, radiology> 10% of intracranial mass lesions are metastasis, 10-38% of patients with systemic cancer have brain metastasis: adults: lung, breast, GU tract, colon/rectum, melanoma, sinuses. children: neuroblastoma, embryonal rhabdomyosarcoma, Wilms tumour. Location: most in middle cerebral artery distribution at the cortex, 20% in posterior fossa. See also: haemorrhagic metastasis. (08 Mar 2000) |
| brain murmur | <neurology> Sounds produced by intracranial aneurysms or arterial venous aneurysms in congenital dysplastic angiomatosis. (05 Mar 2000) |