| 영문 | brain tumor | 한글 | 뇌종양 |
|---|---|---|---|
| 설명 | 뇌종양이란 뇌와 뇌조직에서 생긴 종양을 지칭하는 말이다. 그러나 대개 넓은 의미로 사용할 경우에는 머리뼈속의 공간인 두개강속에 생기는 모든 종양을 이르는 말로 사용된다. 뇌종양은 한정된 공간인 두개강에서 발생하므로 종양이 그다지 크지 않아도 정상적인 조직을 압박하게 되고, 두개강내의 압력을 높인다. 이런 특징에 의해서 뇌종양의 증상은 다른 종양과 달리, 종양 그 자체의 증상보다도 두개내압상승과 정상조직의 압박에 의한 증상이 많다. 두개내압(뇌압)의 상승에 의한 증상으로는 두통, 구토등이 있으며, 지속적인 뇌압상승에 의해서 유두부종(papilledema)이 관찰되기도 한다. 그리고 정상적인 뇌조직의 압박과 종양이 생긴 부위의 기능의 결합에 뇌의 그 부분에 해당하는 기능의 상실을 보게된다. |
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| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| AER | abduction/external rotation; acoustic evoked response; acute exertional rhabdomyolysis; agranular en... |
|---|---|
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| BEP | brain evoked potential; basic element of performance |
| MAP | malignant atrophic papulosis; mandibular angle plane; maturation-activated protein; maximal aerobic ... |
| NBS | N-bromosuccinimide; National Bureau of Standards; neuroblastoma supressor; nevoid basal cell carcino... |
| evoked response audiometry | A type of electrophysiologic audiometry in which electrical potentials of neural impulses from the cochlear nerve and various levels in the brain in response to acoustic stimulation are used to localise the site of a lesion causing a hearing loss. (05 Mar 2000) |
|---|---|
| peripheral blood stem cell transplantation | A procedure that is similar to bone marrow transplantation. Doctors remove healthy immature cells (stem cells) from a patient's blood and store them before the patient receives high-dose chemotherapy and possibly radiation therapy to destroy the leukaemia cells. The stem cells are then returned to the patient, where they can produce new blood cells to replace cells destroyed by the treatment. (12 Dec 1998) |
| pipe stem cirrhosis | Cirrhosis of the liver with finger-like fibrosis predominantly around portal tracts, seen in schistosomiasis. Leads to portal hypertension but rarely to functional failure of the liver. (05 Mar 2000) |
| pluripotent stem cell | <haematology> Cells in a stem cell line capable of differentiating into several different final differentiated types, for example there may be a pluripotent stem cell line for erythrocytes, granulocytes and megakaryocytes. (11 Mar 1998) |
| haematopoietic stem cell mobilization | The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantion. Haematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization. (12 Dec 1998) |
| haematopoietic stem cells | Progenitor cells from which all blood cells derive. (12 Dec 1998) |
| haematopoietic stem cell transplantation | The transference of stem cells from one animal or human to another (allogeneic), or within the same individual (autologous). The source for the stem cells may be the bone marrow or peripheral blood. Stem cell transplantation has been used as an alternative to autologous bone marrow transplantation in the treatment of a variety of neoplasms. (12 Dec 1998) |
| haemopoietic stem cell | <haematology> Cell that gives rise to distinct daughter cells, one a replica of the stem cell, one a cell that will further proliferate and differentiate into a mature blood cell. Pluripotent stem cells can give rise to all lineages, committed stem cells (derived from the pluripotent stem cell) only to some. (18 Nov 1997) |
| hematopoietic stem cell | <haematology> Cell that gives rise to distinct daughter cells, one a replica of the stem cell, one a cell that will further proliferate and differentiate into a mature blood cell. Pluripotent stem cells can give rise to all lineages, committed stem cells (derived from the pluripotent stem cell) only to some. (18 Nov 1997) |
| stem | The main stem or a branch of the main axial system of a plant, developed from the plumule of the embryo and typically bearing leaves. (09 Oct 1997) |
| stem and loop structure | <molecular biology> The structure of tRNAs is so termed because it has four base paired stems and three loops (not base paired), one of which contains the anticodon. (18 Nov 1997) |
| stem bronchus | The main bronchus from which the branches of the bronchial tree arise. (05 Mar 2000) |
| stem cell | 1. Cell that gives rise to a lineage of cells. Particularly used to describe the most primitive cells in the bone marrow from which all the various types of blood cell are derived. 2. More commonly used of a cell that, upon division, produces dissimilar daughters, one replacing the original stem cell, the other differentiating further (e.g. Stem cells in basal layers of skin, in haematopoetic tissue and in meristems). (13 Nov 1997) |
| stem cell factor | <growth factor> Haemopoietic growth factor 18.6 kD from sequence, found as dimer (35 kD protein, 53 kD in its glycosylated form). Acronym: SCF (18 Nov 1997) |
| stem cell growth factors | <growth factor> Compounds, usually proteins, that make stem cells grow faster. (26 Mar 1998) |